Citations

Full opinion text

MEMORANDUM AND ORDER YOUNG, District Judge. I. INTRODUCTION A group of wholesale drug distributors (the “Direct Purchasers”) and health and welfare benefit funds (the “End-Payors” ) (collectively, the “Plaintiffs”), on behalf of themselves and all others similarly situated, brings this multidistrict, putative class action against AstraZeneca AB, Aktiebolaget Hassle, and AstraZeneca LP (collectively, “AstraZeneca”), Ranbaxy Pharmaceuticals, Inc., Ranbaxy Inc., and Ranbaxy Laboratories Ltd. (collectively, “Ranbaxy”); Teva Pharmaceutical Industries, Ltd. and Teva Pharmaceuticals USA, Inc. (collectively, “Teva”); and Dr. Reddy’s Laboratories Ltd. and Dr. Reddy’s Laboratories, Inc. (collectively, “Dr. Reddy’s”) (collectively, with Ranbaxy and Teva, the “Generic Defendants”) (collectively, with AstraZeneca, the “Defendants”) for alleged violations of state and federal antitrust laws. Specifically, the Plaintiffs contend that AstraZeneca and each of the three Generic Defendants entered into reverse payment agreements to keep generic versions of AstraZeneca’s heartburn medication — sold under the brand name Nexium — out of the market, thereby facilitating the extraction of supracompetitive rents by virtue of AstraZeneca’s artificially secured monopoly market position. The Defendants filed five motions to dismiss the Plaintiffs’ claims under Federal Rule of Civil Procedure 12(b)(6) (“Rule 12(b)(6)”). The key issues in these motions can be subdivided into two groups: those relating to the Direct Purchasers and those relating to the End-Payors. With respect to the Direct Purchasers, the Defendants argue that (1) the exclusionary conduct at issue falls within the scope of AstraZeneca’s Nexium-related patents, so no action for antitrust liability may lie; and (2) even if antitrust liability would otherwise attach to the Defendants’ conduct, (a) the doctrine of Noerr-Pennington renders the challenged agreements immune from antitrust scrutiny and (b) the Direct Purchasers’ challenge to the particular agreement between AstraZeneca and Ranbaxy is time-barred under the relevant federal statute of limitations. With respect to the End-Payors, the Defendants argue that (1) the applicable state-specific statutes of limitations bar the End-Payors’ claims with respect to the agreement between AstraZeneca and Ranbaxy; (2) the End-Payors lack standing under both Article III and Federal Rule of Civil Procedure 23 (“Rule 23”) to bring their claims; and (3) the End-Payors’ claims brought under the antitrust laws of eight states (Arizona, Illinois, Mississippi, New York, South Dakota, Tennessee, Utah, and West Virginia) and Puerto Rico and the consumer protection statutes of two states (Massachusetts and North Carolina) are deficient for various reasons. At a motion hearing held on April 18, 2013, the Court denied all of the Defendants’ motions and asked for further briefing on the viability of the End-Payors’ Rule 23 standing and claims under Illinois law. Upon reflection, however, the Court acknowledges that it may have acted hastily on some of the matters presented and, therefore, takes the time here to revisit some of its earlier conclusions. Moreover, at the time of the motion hearing, the parties — and, quite frankly, the Court— were waiting with bated breath for the Supreme Court’s decision in Federal Trade Commission v. Actavis, — U.S.—, 133 S.Ct. 2223, 186 L.Ed.2d 343 (2013), which was anticipated to have significant implications for the instant case by resolving fundamental questions concerning the lawfulness of reverse payment agreements. Therefore, although the Court has no reason to modify its judgment with respect to the Defendants’ motion to dismiss the Direct Purchasers’ claims, the recent arrival of Actavis compels the Court to adjust its rationale in light of that opinion. Finally, armed with additional briefing supplied by the parties, the Court is now prepared to rule on the Rule 23 standing and Illinois law issues left unaddressed at the motion hearing. A. Procedural Posture The End-Payors filed a consolidated complaint on February 1, 2013, Corrected Consol. Am. Class Action Compl. & Demand Jury Trial (“End-Payors’ Compl.”), ECF No. 114, after the Court was called upon to intercede in a dispute over which of the parties’ attorneys would serve as lead class counsel, see In re Nexium, (Esomeprazole) Antitrust Litig., No. 12-md-02409-WGY, 2013 WL 326215 (D.Mass. Jan. 24, 2013). One month later, on March 1, 2013, the Defendants filed their motion to dismiss the End-Payors’ consolidated complaint, Defs.’ Mot. Dismiss Indirect Purchasers’ Consol. Am. Compl., ECF No. 155, together with their supporting memorandum of law, Defs.’ Mem. Supp. Their Mot. Dismiss Indirect Purchasers’ Consol. Am. Compl. (Dkt. No. 114) Pursuant Fed. Rule Civil Procedure 12(b)(6) (“Defs.’ Mot. Dismiss End-Payors”), ECF No. 156. The End-Payors filed their memorandum in opposition to the Defendants’ motion to dismiss on March 22, 2013. End-Payor Class Pis’ Mem. Opp’n Defs.’ Mot. Dismiss (“End-Payor’s Mem. Opp’n”), ECF No. 189. The Defendants filed their reply to the End-Payors’ opposition in further support of their motion on April 5, 2013. Defs.’ Reply Mem. Further Supp. Their Mot. Dismiss Indirect Purchasers’ Consol. Am. Compl. (Dkt. No. 114) Pursuant Fed. Rule Civil Procedure 12(b)(6) (“Defs.’ Reply End-Payors”), ECF No. 208. The Direct Purchasers, for their part, filed a consolidated complaint with this Court on February 21, 2013. Consol. Am. Compl. & Demand Jury Trial (“Direct Purchasers’ Compl.”), ECF No. 131. The following day, each of the Defendants separately moved to dismiss the Direct Purchasers’ complaint, appending to their respective motions memoranda of law in support. Mot. Dr. Reddy’s Labs. Dismiss Direct Purchasers’ Consol. Am. Compl., ECF No. 132; Mem. Supp. Mot. Dr. Reddy’s Labs. Dismiss Direct Purchasers’ Consol. Am. Compl. (“Dr. Reddy’s Mem.”), ECF No. 133; AstraZeneca Defs.’ Mot. Dismiss Direct Purchasers’ Consol. Am. Compl., ECF No. 134; AstraZeneca Defs.’ Mem. Supp. Their Mot. Dismiss Direct Purchasers’ Consol. Am. Compl. (Dkt. No. 131) Pursuant Fed. Rule Civil Procedure 12(b)(6) (“AstraZeneca’s Mem.”), ECF No. 135; Teva Defs.’ Mot. Dismiss, ECF No. 136; Teva Defs.’ Mem. Supp. Its Mot. Dismiss Direct Purchaser Pis.’ Consol. Am. Compl. (“Teva’s Mem.”), ECF No. 137; Def. Ranbaxy’s Mot. Dismiss Direct Purchasers’ Consol. Am. Compl., ECF No. 138; Def. Ranbaxy’s Mem. Law Supp. Its Mot. Dismiss Direct Purchasers’ Consol. Am. Compl. (“Ranbaxy’s Mem.”), ECF No. 139. On March 15, 2013, the Direct Purchasers filed four memoranda in opposition to each of the Defendants’ motions to dismiss. Direct Purchaser Class Pis.’ Opp’n Dr. Reddy’s Mot. Dismiss, ECF No. 167; Direct Purchaser Class Pis.’ Opp’n AstraZeneca’s Mot. Dismiss (“Direct Purchasers’ Opp’n AstraZeneca’s Mot. Dismiss”), ECF No. 168; Direct Purchaser Class Pis.’ Opp’n Teva’s Mot. Dismiss (“Direct Purchasers’ Opp’n Teva’s Mot. Dismiss”), ECF No. 169; Direct Purchaser Class Pis.’ Opp’n Ranbaxy’s Mot. Dismiss (“Direct Purchasers’ Opp’n Ranbaxy’s Mot. Dismiss”), ECF No. 170. AstraZeneca filed a reply in further support of its motion to dismiss on March 29, 2013, AstraZeneca Defs.’ Reply Mem. Further Supp. Mot. Dismiss Direct Purchasers’ Consol. Am. Compl. (Dkt. No. 131) Pursuant Fed. Rule Civil Procedure 12(b)(6), ECF No. 194, and on April 1, 2013, the Generic Defendants followed suit, Reply Mem. Law Supp. Def. Ranbaxy’s Mot. Dismiss Direct Purchasers’ Consol. Am. Compl. (“Ranbaxy’s Reply”), ECF No. 199; Reply Supp. Mot. Dr. Reddy’s Labs. Dismiss Direct Purchasers’ Consol. Am. Compl., ECF No. 200; Teva Defs.’ Reply Mem. Supp. Their Mot. Dismiss Direct Purchaser Pis.’ Consol. Am. Compl., ECF No. 201. At a motion hearing held on April 18, 2013, the Court denied all of the Defendants’ motions, Elec. Clerk’s Notes, Apr. 18, 2013, ECF No. 218, and requested further briefing on the End-Payors’ Rule 23 standing and claims under Illinois law, Mot. Hr’g Tr. 42:16-17, Apr. 18, 2013, ECF No. 216. Per the Court’s instructions, the parties submitted briefs on these two issues on May 2, 2013. Defs.’ Supplemental Mem. Supp. Their Mot. Dismiss Indirect Purchasers’ Consol. Am. Compl. (Dkt. No. 114) Pursuant Fed. Rule Civil Procedure 12(b)(6) (“Defs.’ Supplemental Mem.”), ECF No. 223; End-Payor Class Pis.’ Supplemental Mem. Opp’n Defs.’ Mot. Dismiss (“End-Payors’ Supplemental Mem.”), ECF No. 224. B. Regulatory and Transactional Background 1. Hatch-Waxman Regime Before a drug manufacturer may market a new drug to the public, it must first seek the approval of the United States Food and Drug Administration (“FDA”) by filing a New Drug Application (“NDA”) with the agency. Actavis, 133 S.Ct. at 2228. The road to NDA approval is long and fraught with expense, as the process requires applicants to submit, inter alia, a description of the proposed drug’s components and composition; reports on the safety and effectiveness of the drug; and an explanation of how the drug will be manufactured, processed, and packaged. See 21 U.S.C. § 355(b)(1). Drugs that have been approved by the FDA are then listed in a publication known colloquially as the “Orange Book.” See Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book), U.S. Food & Drug Admin., http://www.fda.gov/Drugs/ InformationOnDrugs/ucml29662.htm (last updated Aug. 23, 2013). The Drug Price Competition and Patent Term Restoration Act of 1984, Pub.L. No. 98-417, 98 Stat. 1585 (codified as amended at 15, 21, 28, and 35 U.S.C.)— known more commonly by its popular title, the “Hatch-Waxman Act,” derived from the surnames of the Act’s principal sponsors — was passed with the express purpose of expediting the entry of noninfringing generic competitors into pharmaceutical drug markets in order to decrease healthcare costs for consumers. See PLI-VA, Inc. v. Mensing, — U.S. —, 131 S.Ct. 2567, 2574, 180 L.Ed.2d 580 (2011). Under the Hatch-Waxman Act, generic drug manufacturers wishing to market a generic version of a brand-name drug need not undertake the extensive and expensive NDA process; instead, they may file an Abbreviated New Drug Application (“ANDA”). Actavis, 133 S.Ct. at 2228. An ANDA must show that the generic drug contains the same active ingredients, route of administration, dosage form, and strength as the brand-name drug, as well as demonstrate that the generic and brand-name drugs are bioequivalent. See 21 U.S.C. § 355(3X2)(A)(ii)-(iv). In addition, an ANDA must contain one of four certifications: (1) that no patent for the brand-name drug has been filed, (2) that the patent for the brand-name drug has expired, (3) that the generic manufacturer will not seek to market its drug before the expiration of the patent for the brand-name drug, or (4) that the patent for the brand-name drug is invalid or will not be infringed by the proposed generic alternative. Id. § 355(j)(2)(A)(vii). Choosing the last of these options, referred to as a “paragraph IV” certification, “automatically counts as patent infringement, and often means provoking litigation.” Actavis, 133 S.Ct. at 2228 (citation omitted) (quoting Caraco Pharm. Labs., Ltd. v. Novo Nordisk AJS, — U.S. —, 132 S.Ct. 1670, 1677, 182 L.Ed.2d 678 (2012)) (internal quotation marks omitted) (citing 35 U.S.C. § 271(e)(2)(A)). To encourage generic manufacturers to bring their drugs to market and assume the potential risk of defending against a patent infringement action, the HatchWaxman Act grants 180 days of market exclusivity to the first generic manufacturer to file an ANDA containing a paragraph IV certification (the “first-filer”), 21 U.S.C. § 355(j)(5)(B)(iv), meaning that the FDA is disallowed from approving ANDAs from competing generic manufacturers for the same drug. The Medicare Prescription Drug, Improvement, and Modernization Act of 2003, Pub.L. No. 108-173, 117 Stat. 2006 (codified as amended at 26 and 42 U.S.C.), however, provides a number of conditions under which a first-filer can forfeit its eligibility for 180-day exclusivity, see 21 U.S.C. § 355(j)(5)(D)(i)(I)-(VI), the most relevant of which for the purposes of this case is the so-called “failure-to-market” provision, see id. § 355(j)(5)(D)(i)(I). Once the first-filer forfeits its 180-day exclusivity, however, no other generic applicant may enjoy such a benefit. See id. § 355(j)(5)(D)(iii)(II). 2. Authorized Generics and No-Authorized Generic Agreements An authorized generic is essentially a bránd-name drug produced by a brand manufacturer but marketed under a generic label. See Sanofi-Aventis v. Apotex Inc., 659 F.3d 1171, 1174 ,(Fed.Cir.2011). Because brand manufacturers have already obtained FDA approval to sell their brand-name drugs, they are free to launch authorized generics during the first-filer’s 180-day exclusivity window in an effort to recoup some of the monopoly profits that are inherently lost by generic market entry. See id. at 1775; Fed. Trade Comm’n, Authorized Generic Drugs: Short-Term Effects and Long-Term Impact i-iv (2011), available at http://www.ftc.gov/os/2011/08/ 201 lgenericdrugreport.pdf [hereinafter FTC Report on Authorized Generics ]. A brand manufacturer may, however, opt to forgo its right to market an authorized generic by entering into a “no-authorized generic” agreement with the first-filer. See Erica N. Andersen, Note, Sphering the Market: Analyzing the Debate over Reverse-Payment Settlements in the Wake of the Medicare Modernization Act of 2003 and In Re Tamoxifen Citrate Litigation, 93 Iowa L.Rev. 1015, 1063 (2008). Such agreements commonly take the form of an exclusive license that allows the first-filer to market a generic version of the brand manufacturer’s brand-name drug during the 180-day exclusivity period. FTC Report on Authorized Generics, supra, at 21. C. Facts Alleged 1. AstraZeneca’s New Drug Application Filing On December 3, 1999, AstraZeneca filed NDA No. 21-153, by which it sought FDA approval to market under the brand name Nexium a proton pump inhibitor (“PPI”) containing esomeprazole magnesium as its active ingredient. End-Payors’ Compl. ¶¶ 64-65. AstraZeneca received the FDA’s approval for its NDA on February 20, 2001. Id. ¶ 65. In conjunction with its NDA, AstraZeneca listed fourteen patents in the FDA Orange Book as relating to Nexium or a way of using Nexium. Id. ¶ 66. 2. The Generics’ Abbreviated Drug Application Filings a. Ranbaxy’s ANDA Filing Four years later, the generic drug manufacturer Ranbaxy filed ANDA No. 77-830 and notified AstraZeneca that it sought to market generic versions of Nexium. Id. ¶ 73. In addition to its notice, Ranbaxy included a certification pursuant to paragraph IV that stated that the commercial manufacture, use, and/or sale of any generic Nexium product would not infringe any of AstraZeneca’s valid patents listed in the Orange Book to the extent that they expired after October 2007. Id. In response, AstraZeneca filed proceedings in the District Court for the District of New Jersey (the “New Jersey District Court”) on November 21, 2005, bringing suit under the Hatch-Waxman Act. Id. ¶ 74. AstraZeneca claimed that Ranbaxy’s generic version of Nexium would infringe six patents — U.S. Patent No. 5,714,504 (the “'504 patent”); U.S. Patent No. 5,877,192 (the “'192 patent”); U.S. Patent No. 6,875,872 (the “'872 patent”); U.S. Patent No. 6,428,810 (the “'810 patent”); U.S. Patent No. 6,369,085 (the “'085 patent”); and U.S. Patent No. 5,948,789 (the “'789 patent”) — including five which were listed in the Orange Book. Id. Although AstraZeneca initiated proceedings against Ranbaxy, the End-Payors allege that AstraZeneca faced a high likelihood that the patents under which AstraZeneca sued would be invalidated once challenged by generic manufacturers. Id. This is because, the End-Payors’ allege, the purported invention of esomeprazole, Nexium’s active ingredient, is “prima facie obvious in light of the prior art,” id. ¶ 67 — that is, it was obvious in light of the information that was already in the public domain, including AstraZeneca’s prior PPI, Prilosec, or so the End-Payors contend, id. b. Teva’s ANDA Filing Several months later, on January 26, 2006, Teva notified AstraZeneca that it had filed ANDA No. 78-003 and sought to market generic versions of Nexium, id. ¶ 77; as part of Teva’s notification, it also included a paragraph IV certification stating that its intentions regarding generic manufacture would not infringe any of AstraZeneca’s valid patents listed in the Orange Book, id. In response, AstraZeneca filed proceedings in the New Jersey District Court on March 8, 2006, bringing suit under the Hatch-Waxman Act. Id. ¶ 78. AstraZeneca claimed that Teva’s generic version of Nexium would infringe five patents listed in the Orange Book. Id. c. Dr. Reddy’s ANDA Filing Later that same year, on August 17, 2006, Dr. Reddy’s filed ANDA No. 78-279 and similarly notified AstraZeneca that it sought to market generic versions of Nexium, id. ¶ 81; as part of Dr. Reddy’s notification, it also included a paragraph TV certification that its intentions regarding generic manufacture would not infringe valid claims based on seven of AstraZeneca’s patents listed in the Orange Book, id. On December 4, 2007, Dr. Reddy’s amended its ANDA to state that it would not infringe the '504, '192, '872 patents, or that they were not valid. Id. Once again, in response, AstraZeneca filed proceedings in the New Jersey District Court on January 17, 2008, bringing suit under the Hatch-Waxman Act. Id. ¶ 82. AstraZeneca claimed that Dr. Reddy’s generic version of Nexium would infringe three patents listed in the Orange Book. Id. 3. AstraZeneca’s Alleged Reverse Payment Agreements With the Generic Defendants a. AstraZeneca’s Alleged Reverse Payment Agreement With Ranbaxy After the parties had completed discovery, but before the New Jersey District Court could enter any rulings on the merits of the case, AstraZeneca allegedly entered into a reverse payment agreement with Ranbaxy on April 14, 2008 (the “AstraZeneca/Ranbaxy Agreement”). Id. ¶ 90. Under this agreement, AstraZeneca agreed to end its proceedings against Ranbaxy, and the court entered a consent judgment (the same day that the thirty-month stay on FDA approval of Ranbaxy’s generic Nexium expired). Id. In consideration for Ranbaxy’s agreeing to (1) admit that the '504, '192, '789, '872, '810, and '085 patents were enforceable and valid; (2) admit that Ranbaxy’s generic Nexium would infringe the '504, '192, '789, and '872 patents; and (3) delay the launch of its generic Nexium until May 27, 2014, AstraZeneca agreed to pay Ranbaxy over $1,000,000,000. Id. ¶¶ 91-92. After Ranbaxy allegedly entered into the reverse payment agreement with AstraZeneca, Malvinder Singh, Ranbaxy’s chief executive officer, purportedly stated that Ranbaxy had secured as much as $1.5 billion in prospective revenue between the commencement of the reverse payment agreement and the end of Ranbaxy’s 180-day period of marketing exclusivity in 2014 envisaged by the agreement. Id. ¶ 93. AstraZeneca, the Plaintiffs allege (upon information and belief), has already handed over millions of dollars to Ranbaxy under their reverse payment agreement. Id.; Direct Purchasers’ Compl. ¶ 120. According to information gleaned from a press release issued two days after the alleged reverse payment agreement, however, the majority of the value accruing to Ranbaxy under the agreement will not become available until 2014. End-Payors’ Compl. ¶ 94. The one billion dollars of value accruing to Ranbaxy, the End-Payors contend, consisted of AstraZeneca’s agreeing to refrain from producing its own authorized generic version of Nexium during the 180-day exclusivity period, a product which would otherwise stand in direct competition with Ranbaxy’s generic Nexium. Id. The End-Payors allege that AstraZeneca and Ranbaxy’s representation of these payments as the grant of an exclusive license, in return for Ranbaxy’s rendering manufacturing and distribution services to AstraZeneca, however, is merely obfuseatory. Id. ¶ 95. In other words, they were structured to disguise the true value that Ranbaxy was conferring on AstraZeneca by virtue of Ranbaxy’s agreement to delay entering the market in competition with Nexium. Id. AstraZeneca, the End-Payors contend, would never have agreed to refrain from competing with Ranbaxy within Ranbaxy’s prospective market for the generic Nexium, nor would it have earmarked Ranbaxy as its supplier of Nexium and authorized generic distributor of two of AstraZeneca’s other PPI drugs, had Ranbaxy not agreed to delay its competition with AstraZeneca for more than six years. Id. Under the terms of AstraZeneca’s alleged reverse payment agreement with Ranbaxy, Ranbaxy’s 180-day market exclusivity period did not begin until May 27, 2014. Id. The End-Payors allege therefore that, were it not for the reverse payment agreement between AstraZeneca and Ranbaxy, Ranbaxy, the first-moving generic manufacturer, could have entered the market several years earlier (and perhaps as early as April 2008). Id. ¶ 75. b. Teva’s and Dr. Reddy’s Attempt to Break the Bottleneck Resulting from the Alleged AstraZeneca/Ranbaxy Reverse Payment Agreement After AstraZeneca and Ranbaxy allegedly entered into their reverse payment agreement, Teva moved for declaratory judgment against AstraZeneca on April 30, 2008. Id. ¶ 96. Teva sought to obtain a ruling of invalidity and noninfringement with respect to the patents listed in the Orange Book as to which AstraZeneca had not commenced proceedings against Teva following Teva’s ANDA filing for its generic version of Nexium. Id. The EndPayors argue that Teva’s motivation for filing its motion for declaratory judgment was to obtain a favorable opinion with respect to all of the Nexium patents AstraZeneca had listed in the Orange Book. Id. Had Teva obtained what it sought, it would have succeeded in “uncork[ing] the FDA approval bottleneck” which had been previously fastened tight when AstraZeneca had settled with the first-filing generic, Ranbaxy. Id. When AstraZeneca sought to dismiss Teva’s motion for declaratory judgment for lack of jurisdiction, Teva accused AstraZeneca of manipulating the Hatch-Waxman regime by trying “to take advantage of what[, in Teva’s view, was] an invalid and illegitimate patent monopoly.” Id. ¶ 97 (emphasis omitted) (internal quotation marks omitted). This is because, were Teva not allowed to challenge AstraZeneca’s Nexium patents, the AstraZeneca/Ranbaxy Agreement would have succeeded in maintaining the bottleneck for six years, which would prevent any generic manufacturer from entering the market despite the suspected invalidity of AstraZeneca’s Nexium patents. Id. c. AstraZeneca’s Alleged Reverse Payment Agreement With Teva Before the court could enter a final judgment in the principal matter concerning Teva’s alleged infringement of AstraZeneca’s patents, however, AstraZeneca allegedly entered into a reverse payment agreement with Teva (the “AstraZeneea/Teva Agreement”), which ended the litigation between the parties. Id. ¶ 99. The End-Payors allege that the parties entered into this agreement on (or about) January 7, 2010. Id. The New Jersey District Court memorialized the agreement in a consent judgment. AstraZeneca’s Mem., Ex. 5, Consent J. (“AstraZeneca/Teva Consent J.”) ¶ 8, at 3-4, ECF No. 135-7. Teva, under the terms of the reverse payment agreement, allegedly agreed to (1) admit that the patents listed in the Orange Book at that time relating to Nexium would be “enforceable and valid with respect to certain products”; (2) admit that its generic Nexium would infringe the '504, '192, '789, '085, and '872 patents, as well as U.S. Patent No. 7,411,070; and (3) delay the launch of its generic Nexium until May 27, 2014. End-Payors’ Compl. 1Í100. For Teva’s part, the End-Payors allege that Teva had “an enormous contingent liability to AstraZeneca.” Id. ¶ 102. This potential liability arose from Teva’s decision on September 9, 2004, to begin manufacturing “at risk” a generic version of AstraZeneca’s Prilosec through its partner, Impax. Id. Teva and Impax together shouldered the risk associated with their generic version of Prilosec. Id. When, in 2008, the Federal Circuit upheld a decision from the Southern District of New York that AstraZeneca’s Prilosec patents were valid and thereby infringed by Impax’s generic, In re Omeprazole Patent Litig., 536 F.3d 1361, 1375 (Fed.Cir.2008), Teva was exposed to the risk of substantial liability. End-Payors’ Compl. ¶ 102. As part of the consideration for the reverse payment agreement, Teva and AstraZeneca allegedly agreed that Teva need only pay an amount to AstraZeneca for its prior infringement of AstraZeneca’s patents that AstraZeneca determined would not be financially significant. Id. The End-Payors allege that AstraZeneca’s forgiveness of a significant portion of Teva’s contingent liability was tantamount to a payment from AstraZeneca to Teva. Id. Whatever the pretextual reasons given for these corporate decisions, the import of AstraZeneca’s agreement with Teva, the End-Payors allege, was to delay generic entry into the market for Nexium until May 27, 2014. Id. ¶ 103. Without Teva’s alleged agreement to delay competition resulting from its launching a generic version of Nexium, the End-Payors contend, AstraZeneca would not have forgiven (so significant a portion of) Teva’s contingent liability. Id. d. AstraZeneca’s Alleged Reverse Payment Agreement With Dr. Reddy’s AstraZeneca allegedly entered into a similar reverse payment agreement with Dr. Reddy’s (the “AstraZeneca/Dr. Reddy’s Agreement”) on January 28, 2011, before the court could enter a final judgment concerning Dr. Reddy’s alleged infringement of AstraZeneca’s Nexium patents. Id. ¶ 104. This brought any Nexium-related litigation between AstraZeneca and Dr. Reddy’s to an end. Id. ■ In consideration for Dr. Reddy’s agreement to refrain from challenging AstraZeneca’s Nexium patents and to defer its launching a generic version of Nexium until May 27, 2014, AstraZeneca allegedly agreed to forgive Dr. Reddy’s contingent liability to AstraZeneca arising from Dr. Reddy’s production of a generic version of AstraZeneca’s Accolate “at risk” in November 2010. Id. ¶¶ 104-106. The EndPayors allege that, after AstraZeneca appealed the court’s decision to grant Dr. Reddy’s motion for summary judgment on the matter of its infringement of AstraZeneca’s Accolate patents, Dr. Reddy’s faced the risk of significant damages in connection with its possible patent infringement. Id. ¶ 106. AstraZeneca’s agreement to forgive this contingent liability, the End-Payors allege, constituted a payment to Dr. Reddy’s. Id. Under the terms of AstraZeneca’s alleged agreement with Dr. Reddy’s, AstraZeneca withdrew its claim against Dr. Reddy’s for infringement of the '085 patent, following which the parties entered a consent agreement endorsed by the court which maintained that Dr. Reddy’s generic Nexium did not infringe the '085 patent. Id. ¶ 83. Dr. Reddy’s filed suit on May 19, 2008, seeking declaratory judgment confirming that its generic Nexium would not infringe the '960, '424, '103, '148, '213, and '810 patents, id. ¶ 84; AstraZeneca admitted in its answer that Dr. Reddy’s generic Nexium would not infringe the '148 or '810 patents, id. The End-Payors allege that the AstraZeneca/Dr. Reddy’s Agreement was designed to foreclose generic entry into the market until AstraZeneca’s patents expired on May 27, 2014. Id. ¶ 107. Had Dr. Reddy’s not agreed to this delay, the End-Payors’ submit, AstraZeneca would never have agreed to drop its case against Dr. Reddy’s. Id. The End-Payors allege that the effect of the AstraZeneca/Teva and AstraZeneca/Dr. Reddy’s Agreements, between AstraZeneca and the second and third ANDA filers, was to ensure that the bottleneck resulting from the AstraZeneca/Ranbaxy Agreement remained securely in place. Id. ¶ 108. 4. Anticompetitive Effects of AstraZeneca’s Alleged Reverse Payment Agreements With the Generic Defendants The End-Payors allege that AstraZeneca’s reverse payment agreements were anticompetitive. Id. ¶ 109. This is because the agreements were designed to deprive the putative class members of a market in which generic drug manufacturers made commercial decisions based upon the strength of drug patents, balanced against the countervailing risks of litigation, free from the distortive influence of brand manufacturers’ payments. Id. ¶110. Such reverse payment agreements, the End-Payors further allege, are inconsistent with the purpose of the Hatch-Wax-man Act, as they enabled AstraZeneca to (1) delay the entry of less expensive generic versions of Nexium, (2) fix the price of Nexium, (3) maintain a monopoly in the United States for Nexium, and (4) allocate the entirety of the market for delayed-release esomeprazole magnesium in the United States to AstraZeneca. Id. Were it not for these reverse payment agreements, the End-Payors allege, a generic ANDA flier would have obtained FDA approval to begin marketing on (or about) April 14, 2008, and it would have been in a position to begin selling its generic version not long thereafter. Id. ¶ 111. After the end of the 180-day exclusivity period granted to this generic ANDA filer, other generics would be permitted to enter the market, resulting in further competition. Id. The End-Payors therefore allege that the Defendants’ action in concert unlawfully allowed AstraZeneca to sell Nexium at supracompetitive prices. Id. ¶ 112. II. ANALYSIS A. Standard of Review To survive a motion to dismiss under Rule 12(b)(6), a complaint must allege facts sufficient “to state a claim to relief that is plausible on its face.” Bell Atl. Corp. v. Twombly, 550 U.S. 544, 570, 127 S.Ct. 1955, 167 L.Ed.2d 929 (2007). The grounds of entitlement to relief set forth in the complaint must constitute “more than labels and conclusions, and a formulaic recitation of the elements of a cause of action will not: do.” Id. at 555, 127 S.Ct. 1955. Nevertheless, a defendant’s burden “is a heavy ■ one when a motion to dismiss is filed.” Stein v. Smith, 270 F.Supp.2d 157, 164 (D.Mass.2003) (Lindsay, J.). In its consideration of a motion to dismiss, the Court is instructed to “accept as true all well-pleaded facts in the complaint and draw all reasonable inferences in favor of the plaintiffs.” Gargano v. Liberty Int’l Underwriters, Inc., 572 F.3d 45, 48 (1st Cir.2009). B. Direct Purchasers’ Claims 1. Legality of Reverse Payment Agreements after Actavis Two of the remaining eleven active Nexium patents are set to expire on May 27, 2014, and the remainder of the active Nexium patents will expire on dates ranging from November 25, 2014, to November 3, 2019. See Direct Purchasers’ Compl. ¶ 73. The Defendants argue that the May 27, 2014, generic market entry date set out in the New Jersey District Court’s consent judgments is the earliest date that any of the patents at issue would have expired and that any alleged anticompetitive effects flowing from the settlement agreements underlying the consent judgments would fall squarely within the term of- AstraZeneca’s otherwise exclusionary period of monopoly patent power. See AstraZeneca’s Mem. 9-10; Teva’s Mem. 13-14; Ranbaxy’s Mem. 8. Until recently, there was deep disagreement among the courts of appeals as to how reverse payment agreements ought be viewed under the law. To wit, one set of circuits followed the “scope-of-the-patent” test (upon which the Defendants’ argument is predicated), which held that “absent sham litigation or fraud in obtaining the patent, a reverse payment settlement is immune from antitrust attack so long as its anticompetitive effects fall within the scope of the exclusionary potential of the patent.” Federal Trade Comm’n v. Watson Pharms., Inc., 677 F.3d 1298, 1312 (11th Cir.2012), rev’d sub nom., Actavis, 133 S.Ct. 2223; accord In re Ciprofloxacin Hydrochloride Antitrust Litig. (“Cipro ”), 544 F.3d 1323, 1336 (Fed.Cir.2008), abrogated by Actavis, 133 S.Ct. 2223; In re Tamoxifen Citrate Antitrust Litig. (“Tamoxifen”), 466 F.3d 187, 212-13 (2d Cir.2006), abrogated by Actavis, 133 S.Ct. 2223. The Third Circuit in In re K-Dur Antitrust Litigation (“K-Dur ”), 686 F.3d 197 (3d Cir.2012), vacated, Merck & Co. v. La. Wholesale Drug Co., — U.S. —, 133 S.Ct. 2849, 186 L.Ed.2d 904 (2013) (mem.), Upsher-Smith Labs., Inc. v. La. Wholesale Drug Co., — U.S. —, 133 S.Ct. 2849, — L.Ed.2d — (2013) (mem.), adopted an alternative, “quick-look” rule-of-reason test that instructs juries to regard reverse payments as “prima facie evidence of an unreasonable restraint of trade, which could be rebutted by showing that the payment[s] (1) [were] for a purpose other than delayed entry or (2) offer[ ] some pro-competitive benefit.” Id. at 218. The Supreme Court was called upon to address this circuit split, and in Actavis, it formally pronounced on the legality of reverse payments. See 133 S.Ct. 2223. In so doing, the Supreme Court rejected the widely followed scope-of-the-patent test. Id. at 2230-34. The Supreme Court did not go so far as to endorse K-Dur’s strict, presumptively-unlawful test, however. Id. at 2237-38. Instead, it adopted a rule-of-reason standard as a middle-of-the-road compromise, the contours of which have been left to the lower courts to etch. See id. Rule-of-reason analysis demands a determination as to “whether under all the circumstances of the case the restrictive practice imposes an unreasonable restraint on competition.” Arizona v. Maricopa Cnty. Med. Soc’y, 457 U.S. 332, 343, 102 S.Ct. 2466, 73 L.Ed.2d 48 (1982). Judges engaging in rule-of-reason analysis are directed to consider three primary factors: (1) whether “the alleged agreement involved the exercise of power in a relevant economic market,” (2) whether “this exercise had anti-competitive consequences,” and (3) whether “those detriments outweighed efficiencies or other economic benefits.” Stop & Shop Supermarket Co. v. Blue Cross & Blue Shield of R.I., 373 F.3d 57, 61 (1st Cir.2004). The Court now weighs each of these factors. 2. Rule-of-Reason Analysis a. Market Power in the Relevant Market The first rule-of-reason criterion to address is whether the Defendants exercised market power in the relevant market. The Defendants argue that the Direct Purchasers have failed to allege a plausible relevant market, see Dr. Reddy’s Mem. 15-17; AstraZeneca’s Mem. 10-17, suggesting that the Court need not even reach the question of whether the Defendants conceivably possess the market power necessary for the Direct Purchasers to state claims against them under the Sherman Act, 15 U.S.C. §§ 1-2. Specifically, the Defendants contend that the Direct Purchasers’ proposed market — namely, brand Nexium and generic equivalents that also share its active ingredient, esomeprazole magnesium — is far too narrow because it excludes other products that are either similar in chemical composition or used to treat comparable medical conditions. Dr. Reddy’s Mem. 15-17 (noting that the Direct Purchasers’ complaint “spends several paragraphs ... describing the similarities in structure between Prilosec (omeprazole) and Nexium (esomeprazole),” id. at 16 (citing Direct Purchasers’ Compl. ¶¶ 75-78)); AstraZeneca’s Mem. 13-17 (noting that the Direct Purchasers’ complaint alleges that other PPIs, as well as H2 blockers and non-prescription antacids, “are used to treat the same or similar conditions” as Nexium, id. at 14 (quoting Direct Purchasers’ Compl. ¶ 71) (internal quotation marks omitted), and that “observed differences in healing rates and symptom relief for Nexium and Prilosec may reflect differences in dose rather than metabolic or pharmacologic differences,” id. at 17 (quoting Direct Purchasers’ Compl. ¶ 89) (internal quotation marks omitted)). The Defendants’ arguments ring hollow upon review of the case law. In order to state a claim under section 1 of the Sherman Act, a plaintiff must demonstrate that “the defendant had market power in the relevant market, and the specific intent to restrain competition.” CVD, Inc. v. Raytheon Co., 769 F.2d 842, 851 (1st Cir.1985). Relatedly, under section 2 of the Sherman Act, a plaintiff must show that “the defendant had the specific intent to monopolize the relevant market, and a dangerous probability of success.” Id. The Supreme Court has declared that, for antitrust purposes, a “relevant market” is made up of “commodities reasonably interchangeable by consumers for the same purposes.” United States v. E.I. du Pont de Nemours & Co., 351 U.S. 377, 395, 76 S.Ct. 994, 100 L.Ed. 1264 (1956). The reasonable interchangeability of a set of products is not dependent on the similarity of their forms or functions; instead, “[s]uch limits are drawn according to the cross-elasticity of demand for the product in question — the extent to which purchasers will accept substitute products in im stances of price fluctuation and other changes.” George R. Whitten, Jr., Inc. v. Paddock Pool Builders, Inc., 508 F.2d 547, 552 (1st Cir.1974); see also Brown Shoe Co. v. United States, 370 U.S. 294, 325, 82 S.Ct. 1502, 8 L.Ed.2d 510 (1962) (“The outer boundaries of a product market are determined by the reasonable interchangeability of use or the cross-elasticity of demand between the product itself and substitutes for it.”). The Direct Purchasers’ complaint expressly alleges that “Nexium does not exhibit significant, positive cross-elasticity of demand with respect to price with any product other than AB-rated generic versions of Nexium.” Direct Purchasers’ Compl. ¶ 145. The fact that other drugs may be used to treat heartburn and related conditions is immaterial to the present inquiry. See, e.g., United States v. Archer-Daniels-Midland Co., 866 F.2d 242, 248 & n. 1 (8th Cir.1988) (concluding that, although high fructose corn syrup and sugar serve near-identical functional purposes, the absence of strong cross-price elasticity between the two products suggested that they were not in fact within the same market). The Supreme Court has held that a properly constituted market may indeed be comprised of a single product, Eastman Kodak Co. v. Image Technical Servs., Inc., 504 U.S. 451, 481-82, 112 S.Ct. 2072, 119 L.Ed.2d 265 (1992), and lower courts across the country have on numerous occasions ruled that both a brand-name drug and its generic analogs can fall within the bounds of a relevant market, see, e.g., In re Terazosin Hydrochloride Antitrust Litig., 352 F.Supp.2d 1279, 1319 n. 40 (S.D.Fla.2005) (deeming a relevant market to be composed of branded and generic terazosin hydrochloride); In re Cardizem CD Antitrust Litig. (“Cardizem”), 105 F.Supp.2d 618, 680-81 (E.D.Mich.2000) (accepting plaintiffs’ contention that branded and generic versions of a heart medication with the chemical compound diltiazem hydrochloride constitute a single market), aff'd, 332 F.3d 896 (6th Cir.2003). Although it may be beyond this Court’s competence to confirm the accuracy of the Direct Purchasers’ characterization of the reasonable interchangeability of brand Nexium with other drugs, such a factually intensive determination is better left for resolution by a jury, see Eastman Kodak, 504 U.S. at 482, 112 S.Ct. 2072 (observing that “[t]he proper market definition ... can be determined only after a factual inquiry into the ‘commercial realities’ faced by consumers,” id. (quoting United States v. Grinnell Corp., 384 U.S. 563, 572, 86 S.Ct. 1698, 16 L.Ed.2d 778 (1966))); Todd v. Exxon Corp., 275 F.3d 191, 199-200 (2d Cir.2001) (explaining that “[b]ecause market definition is a deeply fact-intensive inquiry, courts hesitate to grant motions to dismiss for failure to plead a relevant product market”), so, by definition, the Defendants’ motions to dismiss cannot be sustained on this ground. Taking the relevant market to be comprised of brand and generic Nexium alone for the purposes of this memorandum, this Court reaches the conclusion that the Direct Purchasers’ complaint alleges more than enough facts to enable a reasonable jury to find that the Defendants exercise market power. Market power can be proven in one of two ways: either by (1) “direct evidence of market power (perhaps by showing actual supra-competitive prices and restricted output)” or by (2) “circumstantial evidence of market power ... [which] show[s] that the defendant has a dominant share in a well-defined relevant market and that there are significant barriers to entry in that market and that existing competitors lack the capacity to increase their output in the short run.” Coastal Fuels of P.R., Inc. v. Caribbean Petroleum Corp., 79 F.3d 182, 196-97 (1st Cir.1996) (citation omitted). This Court need not engage in an extensive analysis of circumstantial evidence of market power because direct evidence of such power is available — the Direct Purchasers have thoroughly alleged that AstraZeneca, in its position as a monopolist, has been able to charge supracompetitive prices for brand Nexium. See Direct Purchasers’ Compl. ¶¶ 143-145, 147-151 (alleging, inter alia, that “Nexium does not exhibit significant, positive cross-elasticity of demand with respect to price with any product other than AB-rated generic versions of Nexium,” id. ¶ 145, and that “AstraZeneca ... sold Nexium at prices well in excess of marginal costs, and substantially in excess of the competitive price, and enjoyed high profit margins,” id. ¶ 148). b. Anticompetitive Consequences The second rule-of-reason criterion to address is whether the Defendants’ exercise of market power generated anticompetitive consequences. The Generic Defendants argue that the Direct Purchasers have failed to allege how the settlement agreements between AstraZeneca and each of the Generic Defendants have caused a cognizable injury to competition. Ranbaxy’s Mem. 12-13; Dr. Reddy’s Mem. 11-15; Teva’s Mem. 17-19. Specifically, the Generic Defendants claim that the Direct Purchasers’ assertion that the Generic Defendants would have entered the market prior to the expiration of the Nexium patents but for the settlement agreements is far too speculative to state an actionable claim. The theories upon which this argument is founded differ slightly among the Generic Defendants: Ranbaxy and 'Teva contend that there is no indication that they would have prevailed in their patent litigations against AstraZeneca or that they would have launched “at-risk” generic versions of Nexium, Ranbaxy’s Mem. 12-14; Teva’s Mem. 17-19, whereas Dr. Reddy’s raises identical arguments with respect to its own patent litigation with AstraZeneca but further contends that Ranbaxy’s first-filing status would nevertheless have precluded it from entering the market at any time before the closing of Ranbaxy’s 180-day exclusivity window (unless Dr. Reddy’s received a favorable court decision and had tentative approval from the FDA). Dr. Reddy’s Mem. 11-15. To state a claim under the federal antitrust laws, a plaintiff must sufficiently allege an “antitrust injury.” Atlantic Richfield Co. v. USA Petroleum Co., 495 U.S. 328, 334, 110 S.Ct. 1884, 109 L.Ed.2d 333 (1990) (emphasis omitted) (quoting Brunswick Corp. v. Pueblo Bowl-O-Mat, Inc., 429 U.S. 477, 489, 97 S.Ct. 690, 50 L.Ed.2d 701 (1977)) (internal quotation mark omitted). An antitrust injury is described as an “injury of the type the antitrust laws were intended to prevent and that flows from that which makes defendants’ acts unlawful.” Id. (quoting Brunswick, 429 U.S. at 489, 97 S.Ct. 690) (internal quotation mark omitted). “[An] injury, although causally related to an antitrust violation, nevertheless will not qualify as ‘antitrust injury’ unless it is attributable to an anti-competitive aspect of the practice under scrutiny.” Id. There is support in the case law for the proposition that allegations waxing poetic on the probability of successful patent invalidity or unenforceability claims and of a proposed would-have-been date of generic market entry that rest upon but-for theories of causation will not suffice to raise a triable antitrust issue. See, e.g., Watson Pharms., 677 F.3d at 1312-13 (“[I]t is simply not true that an infringement claim that is ‘likely’ to fail actually will fail.... Rational parties settle to cap the cost of litigation and to avoid the chance of losing.”); In re Ciprofloxacin Hydrochloride Antitrust Litig. (“Cipro”), 261 F.Supp.2d 188, 199-202 (E.D.N.Y.2003) (holding that plaintiffs’ allegations that brand defendant’s patent was invalid or unenforceable and that brand defendant “paid enormous sums of money to avoid a judicial determination of the patent infringement case,” id. at 200, were not enough to state a triable claim). Certain authority cuts the other way, however. See, e.g., Andrx Pharms., Inc. v. Biovail Corp. Int'l, 256 F.3d 799, 804, 808-09 (D.C.Cir.2001) (“One can fairly infer from [the agreement providing for the payment of $10 million per quarter to a generic manufacturer] ... that but for the Agreement, [the generic manufacturer] would have entered the market.” Id. at 809). Moreover, the fact that each of the Generic Defendants have launched at-risk products in the past, see Direct Purchasers’ Opp’n Teva’s Mot. Dismiss 11 & nn. 44-47, would seem to undermine the notion that they would not have done so in this case. Finally, in response to Dr. Reddy’s separate allegation regarding first-filers, courts have looked with particular skepticism upon agreements that allow first-filers to exploit their 180-day exclusivity period by prohibiting other generic competitors from entering the market without a demonstrated intention to market them generic drug. See, e.g., Watson Pharms., 677 F.3d at 1311 (noting that a settlement whose purpose is to facilitate a bottleneck in generic market entry would “create[] anticompetitive effects beyond the scope of the patent”); Andrx Pharms., 256 F.3d at 809 (“Although it is true that the first to file an ANDA is permitted to delay marketing as long as it likes, the statutory scheme does not envision the first applicant’s agreeing with the patent holder of the pioneer drug to delay the start of the 180-day exclusivity period.”). Part III of the Supreme Court’s opinion in Actavis added an additional gloss to standard antitrust-injury analysis, however. There, the Supreme Court explained a rule-of-reason approach to reverse payment agreements is preferable to quick-look treatment because “the likelihood of a reverse payment bringing about anticompetitive effects depends upon its size, its scale in relation to the payor’s anticipated future litigation costs, its independence from other services for which it might represent payment, and the lack of any other convincing justification.” 133 S.Ct. at 2237. In other words, only those reverse payment agreements whose anti-competitive consequences are sufficiently great and sufficiently unrelated to the settlement of a particular patent dispute will be censured by the courts. In the instant case, the Plaintiffs allege that AstraZeneca agreed to pay over $1,000,000,000 to Ranbaxy and enter into a no-authorized generic agreement with it, see End-Payors’ Compl. ¶¶ 92, 94, which seems like outsize accommodation from a company to whom Ranbaxy was purportedly liable for patent infringement. It is also alleged that Teva and Dr. Reddy’s were forgiven by AstraZeneca of contingent liabilities tied to their infringement of AstraZeneca’s patents in Prilosec and Accolate, respectively, see id. ¶¶ 102-106, which is entirely disconnected from AstraZeneca’s earlier Nexium-related suits against these parties. Moreover, as section II.B.1.C explains, there exists no persuasive procompetitive justification for the alleged agreements at issue. Taking all intendments in the light most favorable to the Direct Purchasers, then, the no-authorized generic agreement between AstraZeneca and Ranbaxy and AstraZeneca’s forgiveness of Teva’s and Dr. Reddy’s contingent liabilities related to the infringement of non-Nexium-related patents sufficiently implicate adverse anticompetitive consequences to allow the Direct Purchasers’ claims to proceed. Yet even if it can be said that the Defendants’ reverse payment agreements were sufficiently anticompetitive, it is not readily apparent that the Direct Purchasers have recourse under the antitrust laws, so the Generic Defendants claim, because the Generic Defendants did not receive any kind of monetary payment from AstraZeneca in exchange for their alleged commitment to stay out of the market. See Dr. Reddy’s Mem. 10 — 11; Teva’s Mem. 14-17; Ranbaxy’s Mem. 8-12. Instead, AstraZeneca and Ranbaxy allegedly entered into a “no-authorized generic agreement” granting Ranbaxy “an exclusive license ... to market generic deIayed-release esomeprazole ‘ magnesium during Ranbaxy’s first-filer 180-day period of generic market exclusivity,” Direct Purchasers’ Compl. ¶ 121, while Teva and Dr. Reddy’s were allegedly forgiven by AstraZeneca of contingent liabilities for past patent infringement, id. ¶¶ 129-130, 133-134. It is true that some courts have opted for a narrow construal of the term “payment.” See, e.g., In re Lamictal Direct Purchaser Antitrust Litig., No. 12-995(WHW), 2012 WL 6725580, at *6 (D.N.J. Dec. 6, 2012) (holding that “the term ‘reverse payment’ is not sufficiently broad to encompass any benefit that may fall to [a generic manufacturer] in a negotiated settlement” and that “[t]he Third Circuit’s K-Dur opinion is directed towards settlements when a generic manufacturer is paid off with money”); Asahi Glass Co. v. Pentech Pharms., Inc., 289 F.Supp.2d 986, 994 (N.D.Ill.2003) (reasoning that “[i]f any settlement agreement is thus to be classified as involving a forbidden ‘reverse payment,’ we shall have no more patent settlements”). This Court need not take the same tack, however. Cf. In re Lipitor Antitrust Litig., No. 3:12-cv-2389 (PGS), 2013 WL 4780496, at *26 (D.N.J. Sept. 5, 2013) (allowing plaintiffs challenging an alleged reverse payment agreement to amend their complaint to include allegations beyond those of a purely monetary nature). Nowhere in Actavis did the Supreme Court explicitly require some sort of monetary transaction to take place for an agreement between a brand and generic manufacturer to constitute a reverse payment. Admittedly, the Supreme Court spoke only to the merits of cash payouts as a quid pro quo for promises of delayed generic market entry. See, e.g., 133 S.Ct. at 2229 (describing a brand manufacturer’s agreement with three generic manufacturers to “pay millions of dollars to each generic”); id. at 2233 (noting that “[i]n reverse payment settlements, ... a party with no claim for damages (something that is usually true of a paragraph IV litigation defendant) walks away with money simply so it will stay away from the patentee’s market”). Yet Actavis only involved a brand manufacturer’s bargain with three generic manufacturers “to pay millions of dollars to each generic,” see id. at 2229, so the Supreme Court’s confined analysis hardly seems surprising. This Court does not see fit to read into the opinion a strict limitation of its principles to monetary-based arrangements alone. Adopting a broader interpretation of the word “payment,” on the other hand, serves the purpose of aligning the law with modern-day realities. c. Weighing Economic Detriments Against Economic Benefits The final rule-of-reason criterion requires the Court to balance the economic detriments of the agreements at issue against the economic benefits thereof. The Defendants have not put forward a shred of affirmative evidence tending to show that the agreements into which they allegedly entered produced any countervailing procompetitive benefits whatsoever. See AstraZeneca’s Mem.; Dr. Reddy’s Mem.; Teva’s Mem.; Ranbaxy’s Mem. The lone conceivable benefit of reverse payment agreements — namely, the settlement of patent disputes — cannot overcome the anticompetitive consequences discussed earlier in section II.B.l.b. See Actavis, 133 S.Ct. at 2234-37 (entertaining a number of arguments against the brand and generic respondents’ position in that case and ultimately holding that “these considerations, taken together, outweigh the single strong consideration — the desirability of settlements — that led the Eleventh Circuit to provide near-automatic antitrust immunity to reverse payment settlements,” id. at 2237). “Where a reverse payment reflects traditional settlement considerations, such as avoided litigation costs or fair value for services, there is not the same concern that a patentee is using its monopoly profits to avoid the risk of patent invalidation or a finding of noninfringement.” Id. at 2236. Such traditional settlement considerations do not appear to be present here, however. Moreover, the presumptive validity accorded to patents upon issuance has been cast in significant doubt by judges and empiricists alike, cf. Lear, Inc. v. Adkins, 395 U.S. 653, 670, 89 S.Ct. 1902, 23 L.Ed.2d 610 (1969) (acknowledging that “the Patent Office is often obliged to reach its decision in an ex parte proceeding, without the aid of the arguments which could be advanced by parties interested in proving patent invalidity”); Fed. Trade Comm’n, Generic Drug Entry Prior to Patent Expiration: An FTC Study 16 (2002), available at http://www.ftc.gov/os/ 2002/07/genericdrugstudy.pdf (finding in a study of the success rate of paragraph IV challenges to brand-drug validity that “[g]eneric applicants prevailed 73 percent of the time”), and although patent holders enjoy broad exclusionary rights, see, e.g., U.S. Const, art. I, § 8, cl. 8 (granting to patent holders “the exclusive Right to their respective Writings and Discoveries” for limited periods of time); Dawson Chem. Co. v. Rohm & Haas Co., 448 U.S. 176, 215, 100 S.Ct. 2601, 65 L.Ed.2d 696 (1980) (echoing “the long-settled view that the essence of a patent grant is the right to exclude others from profiting by the patented invention”), these rights are not limitless, see, e.g., Standard Oil Co. (Ind.) v. United States, 283 U.S. 163, 169, 51 S.Ct. 421, 75 L.Ed. 926 (1931) (“The limited monopolies granted to patent owners do not exempt them from the prohibitions of the Sherman Act and supplementary legislation.”). Accordingly, this Court holds that the Direct Purchasers have pled facts sufficient at the motion-to-dismiss stage to establish violations of sections 1 and 2 of the Sherman Act under the rule of reason. 3. Exceptions to Antitrust Liability The Defendants contend that even if their actions are deemed anticompetitive, (1) all of the agreements between AstraZeneca and the Generic Defendants ought enjoy Noerr-Pennington immunity, see AstraZeneca’s Mem. 4-8; and (2) the relevant statute of limitations bars any Sherman Act claims arising out of the AstraZeneca/Ranbaxy agreement, Ranbaxy’s Mem. 5-6; see also AstraZeneca’s Mem. 17-20. The Court addresses each of these contentions in turn. a. Noerr-Pennington Immunity The Noerr-Pennington doctrine grants antitrust immunity to persons and organizations who, with the intent to restrain trade and diminish competition, act in concert to petition the government to adopt laws and implement policies that are anticompetitive in nature. See Allied, Tube & Conduit Corp. v. Indian Head, Inc., 486 U.S. 492, 499, 108 S.Ct. 1931, 100 L.Ed.2d 497 (1988). Although it originally arose in the context of an individual’s right to entreat the legislature and the executive, see United Mine Workers of Am. v. Pennington, 381 U.S. 657, 669-70, 85 S.Ct. 1585, 14 L.Ed.2d 626 (1965); Eastern R.R. Presidents Conference v. Noerr Motor Freight, Inc., 365 U.S. 127, 136, 81 S.Ct. 523, 5 L.Ed.2d 464 (1961), the doctrine has since been deemed to cover advocacy before all organs of government, including, most relevantly for the present inquiry, courts, see, e.g., California Motor Transp. Co. v. Trucking Unlimited, 404 U.S. 508, 510, 92 S.Ct. 609, 30 L.Ed.2d 642 (1972). Moreover, the Supreme Court has held that the Noerr-Pennington doctrine extends not only to “direct” petitioning but also to activities that are “ ‘incidental’ to a valid effort to influence governmental action.” Allied Tube, 486 U.S. at 499, 108 S.Ct. 1931 (quoting Noerr, 365 U.S. at 143, 81 S.Ct. 523). Ultimately, though, “[t]he scope of [Noerr-Pennington’s] protection depends ... on the source, context, and nature of the anticompetitive restraint at issue.” Id. Writing on behalf of all of the Defendants, AstraZeneca argues that because the New Jersey District Court entered consent judgments sanctioning settlement agreements struck between AstraZeneca and each of the three Generic Defendants, any anticompetitive harms that flow from such agreements are properly attributable to governmental — not private — action. See AstraZeneca’s Mem. 5-6. For support, AstraZeneca contends that the settlement agreements (1) imposed upon the Defendants only the obligation “to file an executed consent judgment in the [New Jersey District Court] within five business days of signing the agreement,” (2) “would become effective only when the consent judgment was entered as an order by the [New Jersey District Court],” and (3) would have been rendered null and void in the event that the Defendants had failed to obtain the New Jersey District Court’s blessing within forty-five days of the date of the consent judgment filings. AstraZeneca’s Mem. 5; see also AstraZeneca’s Mem., Ex. 1, Settlement Agreement (“AstraZeneca/Ranbaxy Settlement Agreement”) §§ 2.1-2.3, at 5-6, ECF No. 157; AstraZeneca’s Mem., Ex. 2, Settlement Agreement (“AstraZeneca/Teva Settlement Agreement”) §§ 2.1-2.3, at 6-7, ECF No. 157-1; AstraZeneca’s Mem., Ex. 3, Settlement Agreement (“AstraZeneca/Dr. Reddy’s Settlement Agreement”) §§ 2.1-2.3, at 6-7, ECF No. 157-2. Moreover, AstraZeneca stresses that it was the New Jersey District Court that formally enjoined the Generic Defendants from offering generic versions of Nexium in the marketplace before May 27, 2014. AstraZeneca’s Mem. 6; see also AstraZeneca’s Mem., Ex. 4, Consent Order & Final J. ¶ 7, ECF No. 135-6; AstraZeneca/Teva Consent J. ¶ 8, at 3-4; AstraZeneca’s Mem., Ex. 6, Consent J. ¶3, at 32, ECF No. 135-8. Courts are largely uniform in their view that private settlement agreements entered into during the pendency of litigation that are neither presented to nor approved by the judge presiding over the dispute fall outside the ambit of NoerrPennington immunity. See, e.g., Andrx Phanns., 256 F.3d at 818-19; Cardizem, 105 F.Supp.2d at 634-36. There is little guidance, however, on the question of whether a judge’s entry of a consent judgment falls squarely within the scope of Noerr-Pennington. A thirteen-year-old law review article published in the Indiana Law Review proposes a sensible analytical approach whose adoption proves useful in determining whether the consent judgments at issue ought be covered under Noerr-Pennington. In the article, Raymond Ku draws upon language in the Supreme Court’s decision in Allied Tube & Conduit Corp. v. Indian Head, Inc., 486 U.S. 492, 108 S.Ct. 1931 — to wit, that “[t]he scope of [NoerrPennington ’s] protection depends ... on the source, context, and nature of the anti-competitive restraint at issue,” id. at 499, 108 S.Ct. 1931 — to create a bidimensional framework: [T]he history of the right to petition and the Supreme Court’s case law demonstrate that immunity is justified based upon the nature of the activity in question and the source of the injury to competition. This Article proposes that immunity attaches when: 1) the conduct represents valid petitioning. Valid petitioning is defined as a formal or informal attempt to persuade an independent governmental decision maker consistent with the rules of the political forum in question, and 2) any anti