Full opinion text
MEMORANDUM AND ORDER YOUNG, District Judge. I. INTRODUCTION This case, arising under the federal antitrust laws and state analogues, presents a challenge to the use of reverse payment settlements in patent litigation. Reverse payment settlements are agreements to settle patent infringement litigation under which the patent holder pays the claimed infringer handsomely to refrain from competing with the patent holder until the patent or patents in suit expire. The arrangement preserves the patent holder’s monopoly and the full term of its patents, while compensating the claimed infringer with at least some of the money it would have earned had it successfully challenged the patents. In a key ruling last year, the Supreme Court held that these kinds of “pay for delay” agreements can, under certain circumstances, violate the federal antitrust laws. Federal Trade Comm’n v. Actavis, Inc., — U.S. -, 133 S.Ct. 2223, 2227, 186 L.Ed.2d 343 (2013). The case at bar, now a multidistrict class action, asks this Court to put the Supreme Court’s holding into practice. This action is brought by a class of wholesale drug distributors (the “Direct Purchasers”), a class of individual consumers, third-party payors, union plan sponsors, and certain insurance companies (the “End-Payors”) (collectively, with the Direct Purchasers, the “Class Plaintiffs”), and a number of pharmaceutical retail outlets: Eckerd Corporation, Giant Eagle, Inc., HEB Grocery Company L.P., JCG (PJC) USA, LLC, The Kroger Co., Maxi Drug, Inc. d/b/a Brooks Pharmacy, Rite Aid Corporation, Rite Aid Headquarters Corp., Safeway Inc., Supervalu, Inc., and Walgreen Co. (collectively, the “Retailer Plaintiffs”) (collectively, with the Direct Purchasers and the End-Payors, the “Plaintiffs”). The Plaintiffs have brought claims for alleged violations of federal and state antitrust laws involving the heartburn medication, Nexium, referred to in its generic form as esomeprazole magnesium, against AstraZeneca AB, Aktiebolaget Hasslé, and AstraZeneca LP (collectively, “AstraZeneca”), Ranbaxy Pharmaceuticals, Inc., Ranbaxy Inc., and Ranbaxy Laboratories, Ltd. (collectively, “Ranbaxy”), Teva Pharmaceutical Industries, Ltd. and Teva Pharmaceuticals USA, Inc. (collectively, “Teva”), and Dr. Reddy’s Laboratories Ltd. and Dr. Reddy’s Laboratories, Inc. (collectively, “DRL”) (collectively, with Ranbaxy and Teva, the “Generic Defendants”) (collectively, with AstraZeneca, the “Defendants”). Beginning in December 2013, the Defendants filed a plethora of motions for summary judgment which the Court decided in January and February of this year. As promised in those summary orders- — -and as urged by Fed.R.Civ.P. 56(a), see Securities Exch. Comm’n v. EagleEye Asset Mgmt., LLC, 975 F.Supp.2d 151 (D.Mass.2013) — the Court- now sets out in full the reasoning for its rulings. A. Procedural Posture This case has had an extensive and tortuous procedural history. Out of necessity, the developments and filings in this case will be reviewed here with a primary focus on the motions for summary judgment being addressed in this opinion. 1. Initial Proceedings and Class Certification On December 7, 2012, six actions pending in the District of Massachusetts, the District of New Jersey, and the Eastern District of Pennsylvania were consolidated into the present multidistrict litigation and assigned to this Court, pursuant to 28 U.S.C. § 1407. See Elec. Notice, Dec. 7, 2012, ECF No.- 1; Transfer Order, MDL No. 2409, ECF No. 2. Representatives for the End-Payors filed a consolidated complaint on February 1, 2013, Corrected Con-sol. Am. Class Action Compl. & Demand Jury Trial (“End-Payors’ Compl.”), ECF No. 114, and representatives for the Direct Purchasers filed their consolidated complaint on February 21, 2013, Consol. Am. Compl. & Demand Jury Trial (“Direct Purchasers’ Compl.”), ECF No. 131. The Defendants filed a number of motions to dismiss these complaints, and the Court” denied all of them at a motion hearing held on April 18, 2013. See Elec. Clerk’s Notes, Apr. 18, 2013, ECF No. 218; see also In re Nexium (Esomeprazole) Antitrust Litig., 968 F.Supp.2d 367 (D.Mass.2013). Several months later, the Court granted two motions certifying an End-Payor damages class, Mem. & Order, Nov. 14, 2013, ECF No. 519, and a Direct Purchaser class, Mem. & Order, Dec. 11, 2013, ECF No. 660. During this time, the Retailer Plaintiffs individually entered this litigation when they collectively filed three amended complaints against the Defendants on November 14, 2013. See Am. Compl. & Demand Jury Trial (“Walgreen Compl.”), ECF No. 515; Am. Compl. & Demand Jury Trial (“Rite Aid Compl.”), ECF No. 516; Am. Compl. & Demand Jury Trial (“Giant Eagle Compl.”), ECF No. 517. 2. Motions for Summary Judgment On December 10, 2013, the Defendants collectively filed eleven motions for summary judgment. See DRL’s Mot. Summ. J. All Claims, ECF No. 594; Teva Defs.’ Mot. Summ. J. Based Absence Reverse Payment Teva, ECF No. 600; Teva Defs.’ Mot. Summ. J. Based Lack Causation, ECF No. 606; Def. Ranbaxy’s Mot. Summ. J. Lack Causation, ECF No. 641; AstraZeneca & Ranbaxy Defs.’ Mot. Summ. J. All Claims Arising AstraZeneca’s Settlement Agreement Ranbaxy, ECF No. 642; AstraZeneca Defs.’ Mot. "Summ. J. All Claims Arising AstraZeneca’s Settlements Teva & DRL, ECF No. 644; AstraZeneca Defs.’ Mot. Summ. J. Basis Causation, ECF No. 645; AstraZeneca, Ranbaxy, & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy, ECF No. 647; AstraZeneca Defs.’ Mot. Summ. J. Direct Purchaser Pis. Lack Actual Injury & Exclude Direct Purchaser Pis.’ Experts’ Damages Opinions, ECF No. 648; AstraZeneca Defs.’ Mot. Partial Summ. J. Basis Statute Limitations, ECF No. 649; AstraZeneca Defs.’ Mot. Summ. J. Barring Assigned Claims, ECF No. 650. The Plaintiffs’ responses came on January 9, 2014. See Direct Purchaser Class Pis.’ Opp’n AstraZeneca Defs.’ Mots. Summ. J. Direct Purchaser Pis.’ & Associated Daubert Mot. Relating “Actual Injury” (ECF No. 648), ECF No. 735; Direct Purchaser Class Pis.’ Opp’n AstraZeneca Defs.’ Mot. Summ. J. Barring Non-Class Direct Purchasers’ Assigned Claims (Dkt. 650), ECF No. 738; Retailer Pis.’ Mem. Opp’n AstraZeneca’s, Ranbaxy’s, & Teva’s Mot. Partial Summ. J. Pis.’ Overall Conspiracy Claim, ECF No. 746; Retailer Pis.’ Mem. Opp’n AstraZeneca & Ranbaxy’s Mot. Summ. J., ECF No. 747; Retailer Pis.’ Mem. Opp’n Teva’s Mot. Summ. J., ECF No. 748; Retailer Pis.’ Mem. Opp’n Dr. Reddy’s’ Mot. Summ. J., ECF No. 749; Retailer Pis.’ Mem. Opp’n AstraZeneca’s Mot. Summ. J. Respect Teva & Dr. Reddy’s Settlements, ECF No. 750; Opp’n Retailer Pis. AstraZeneca’s Mot. Summ. J. Barring Assigned Claims, ECF No. 753; Opp’n Retailer Pis. AstraZeneca’s Mot. Summ. J. Direct Purchaser Pis. Lack Actual Injury & Exclude Direct Purchaser Pis.’ Expert Damages Opinions, ECF No. 761; Retailer Pis.’ Mem. Opp’n Teva’s Mot. Summ. J. Based Lack Causation, ECF No. 762; Retailer Pis.’ Opp’n AstraZeneca Defs.’ Mot. Summ. J. Statute Limitations, ECF No. 765; Direct Purchaser & End-Payor Class Pis.’ Mem. Opp’n Teva Defs.’ Mot. Summ. J. Based Absence Reverse Payment (ECF No. 600), ECF No. 770; Direct Purchaser & End-Payor Class Pis.’ Opp’n AstraZeneca’s Mot. Summ. J. All Claims Arising AstraZeneca’s Settlements Teva & DRL (ECF No. 644), ECF No. 771; Direct Purchaser & End-Payor Class Pis.’ Opp’n DRL’s Mot. Summ. J. (ECF No. 594), ECF No. 772; Retailer Pis.’ Mem. Opp’n Ranbaxy’s Mot. Summ. J. Based Causation, ECF No. 773; Direct Purchaser & End-Payor Class Pis.’ Opp’n AstraZeneca & Ranbaxy Defs.’ Mot. Summ. J. All Claims Arising AstraZeneca’s Settlement Agreement Ranbaxy, ECF No. 779; Retailer Pis.’ Mem. Opp’n AstraZeneca Defs.’ Mot. Summ. J. Basis Causation, ECF No. 781; Direct Purchaser & End-Payor Class Pis.’ Opp’n AstraZeneca, Ranbaxy & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy (ECF No. 647) & Portion DRL’s Mot. Summ. J. (ECF No. 594), ECF No. 784; Direct Purchaser & End-Payor Class Pis.’ Opp’n [606] Teva’s Mot. Summ. J. Based Lack , Causation, ECF No. 789; Direct Purchaser & End-Payor Class Pis.’ Opp’n AstraZeneca’s Mot. Summ. J. Causation, ECF No. 790; Direct Purchaser Class & End Payor Class Pis.’ Opp’n Ranbaxy’s Mot. Summ. J. Due Lack Causation, ECF No. 791. On January 13, 2014, the Court denied AstraZeneca’s ECF No. 648 motion seeking summary judgment against the Direct Purchasers and Retailer Plaintiffs for lack of actual injury and seeking exclusion of testimony from two experts. Elec. Order, Jan. 13, 2014, ECF No. 801. The Court also denied AstraZeneca’s ECF No. 649 motion for partial summary judgment seeking to bar the Retailer Plaintiffs on the basis of statute of limitations. Elec. Order, Jan. 13, 2014, ECF No. 802. Shortly thereafter, on January 16 and 17, 2014, the Defendants filed replies in further support of their surviving motions. See Teva Defs.’ Reply Supp. Mot. Summ. J. [ECF No. 600] Based Absence Reverse "Payment Teva, ECF No. 814; Teva Defs.’ Reply Supp. Mot. [ECF No. 606] Summ. J. Based Lack Causation, ECF No. 815; Reply Supp. AstraZeneca, Ranbaxy, & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy, ECF No. 816; Reply Mem. Supp. AstraZeneca Defs.’ Mot. Summ. J. All Claims Arising AstraZeneca’s Settlements Teva & DRL, ECF No. 817; AstraZeneca’s Reply Mem. Further Supp. Mot. Summ. J. Barring Assigned Claims [Docket No. 650], ECF No. 818; Reply Mem. Supp. DRL’s Mot. Summ. J., ECF No. 819; Reply Mem. Supp. AstraZeneca & Ranbaxy Defs.’ Mot. Summ. J. All Claims Arising AstraZeneca’s Settlement Agreement Ranbaxy, ECF No. 820; Reply Mem. Supp. AstraZeneca Defs.’ Mot. Summ. J. Basis Causation, ECF No. 821; Def. Ranbaxy’s Reply Supp. Mot. Summ. J. Due Lack Causation, ECF No. 823. The Court heard oral argument on five of the Defendants’ motions on January 21, 2014. Elec. Clerk’s Notes, Jan. 21, 2014, ECF No. 846. The five motions argued were: (1) DRL’s ECF No. 594 motion seeking summary judgment on all claims’, (2) Teva’s ECF No. 600 motion seeking summary judgment because of the purported absence of a reverse payment made to Teva, (3) Ranbaxy’s ECF No. 641 motion seeking summary judgment due to a purported lack of causation, (4) AstraZeneca’s ECF No. 642 motion seeking summary judgment on claims arising from its settlement with Ranbaxy, and (5) AstraZeneca, Ranbaxy, and Teva’s ECF No. 647 motion seeking partial summary judgment on the issue of overall conspiracy. Id. At that hearing, the Court denied from the bench the final of these five motions, regarding the existence of an overall conspiracy, and took all remaining motions under advisement. Id. .On February 12, 2014, the Court issued an order laying out its rulings on all eleven motions for summary judgment. See Order, Feb. 12, 2014, ECF No. 857. In light of the aggregate effect of these rulings on the Plaintiffs’ claims, the Court administratively closed this case until the publication of this written opinion explaining its reasoning. Id. 3. Motions for Reconsideration The case was reopened, however, upon the filing of a number of motions for reconsideration on February 28, 2014. See Pis.’ Mot. Rule 6(b)(1)(B) & (2) Reconsideration Teva’s Mot. Summ. J. Based Absence Reverse Payment Teva (ECF No. 600) & AstraZeneca’s Mot. Summ. J. All Claims Arising AstraZeneca’s Settlements Teva & DRL (ECF No. 644); & Pis.’ Opp’n Teva’s Supplemental Br. Based New McGuire Report (ECF No. 855), ECF No. 864; Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation (ECF # 641, 645) Based New Evidence, ECF No. 867; Direct Purchaser Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation (ECF # 641, 645) Based Payment-Free Settlement, ECF No. 870; End-Payor Pis.’ Joinder Direct Purchaser Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation, ECF No. 872. The Court entered an order on March 7, 2014, denying all but two of the motions for reconsideration and scheduling oral argument on (1) the Plaintiffs’ ECF No. 864 motion to reconsider the Court’s grant of summary judgment to Teva based on the absence of a reverse payment and the Court’s grant of summary judgment to AstraZeneca on claims arising from its settlements with Teva and DRL, and (2) the Plaintiffs’ ECF No. 867 motion to reconsider the Court’s grant of summary judgment to AstraZeneca and Ranbaxy due to a lack of causation. Order, Mar. 7, 2014, ECF No. 874. Oppositions to the two surviving motions for reconsideration followed on March 20, 2014. See Teva’s Opp’n Pis.’ Mot. Reconsideration Court’s Grant Summ. J. Based Absence Reverse Payment Teva, ECF No. 877; AstraZeneca’s Opp’n Pis.’ Mot. Reconsideration AstraZeneca & Ranbaxy’s Mots. Summ. J. Due Lack Causation (ECF # 641, 645) Based New Evidence, ECF No. 879; AstraZeneca’s Opp’n Pis.’ Mot. Reconsideration AstraZeneca & Ranbaxy’s Mots. Summ. J. Due Lack Causation (ECF # 641, 645) Based New Evidence, ECF No. 881; Ranbaxy’s Opp’n Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation Based New Evidence, ECF.No. 882. The Plaintiffs filed reply briefs in further support of their motions for reconsideration on March 27, 2014. Pis.’ Reply Ranbaxy’s Opp’n Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation Based New Evidence, ECF No. 889; Pis.’ Reply AstraZeneca’s Opp’n Pis.’ Mot. Reconsideration AstraZeneca’s & Ranbaxy’s Mots. Summ. J. Due Lack Causation Based New Evidence, ECF No. 890. On March 4, 2014, the Court heard oral argument on the two motions for reconsideration and took them under advisement. Elec. Clerk’s Notes, Apr. 4, 2014, ECF No. 896. At an interim pretrial conference held on April 16, 2014, the Court announced its rulings (1) granting the Plaintiffs’ ECF No. 864 motion for reconsideration of summary judgment regarding the absence of a reverse payment to Teva, (2) granting in part the Plaintiffs’ ECF No. 864 motion for reconsideration of AstraZeneca’s motion for summary judgment on claims arising from its settlements with Teva and DRL, with the Court’s reconsideration being limited to AstraZeneca’s settlement with Teva, and (3) denying the Plaintiffs’ ECF No. 867 motion for reconsideration of summary judgment to AstraZeneca and Ranbaxy for lack of causation. See Elec. Clerk’s Notes, Apr. 16, 2014, ECF No. 902; Elec. Endorsement, June 4, 2014, ECF No. 940. Accordingly, the case was reopened and set for trial in October 2014, with a final pretrial conference set to take place in September 2014. Elec. Clerk’s Notes, Apr. 16, 2014; see also Case Reopened, Apr. 17, 2014, ECF No. 903. A final flurry of activity relating to the issue of overarching conspiracy has occurred since the case reopened. On April 22, 2014, DRL filed a motion for reconsideration of the Court’s denial of summary judgment as to overarching conspiracy. DRL’s Mot. Reconsideration, ECF No. 905. The Plaintiffs opposed on May 6, 2014. Pis. Mem. Opp’n DRL’s Mot. Reconsideration (ECF 905), ECF No. 914. The Court denied DRL’s motion on May 9, 2014. Elec. Order, May 9, 2014, ECF No. 916. The Defendants have most recently filed supplemental authority for their argument that the overarching conspiracy claims must fail: a recently published opinion by Judge Mitchell S. Goldberg of the Eastern District of Pennsylvania on issues similar to those before this Court. See King Drug Co. of Florence, Inc. v. Cephalon, Inc., Civil Action Nos. 2:06-cv-1797, 2:06-cv-1833, 2:06-cv-2768, 2014 WL 2813312 (E.D.Pa. June 23, 2014); see also Defs.’ Submission Supplemental Authority Relating Pis.’ Overarching Conspiracy Claims, ECF No. 955. The Plaintiffs’ response was filed on July 2, 2014. Direct Purchaser Class Pis.’ Response Defs.’ Submission Supp. Authority Relating Pis.’' Overarching Conspiracy Claims, ECF No. 960. B. Regulatory and Factual Background In addition to having a complicated procedural history, this case implicates a large and complex body of facts. Although some of this background has been laid out in the Court’s opinion dealing with the Defendants’ prior motions to dismiss, see In re Nexium, 968 F.Supp.2d at 376-78, further review of the regulatory and factual background is required here. Where appropriate, additional facts pertinent to the Court’s analysis will be set out within the relevant sections. 1. Regulatory Framework When a pharmaceutical manufacturer seeks to introduce a new brand-name prescription drug to the U.S. market, it must file a New Drug Application with the United States Food and Drug Administration (“FDA”) and undergo a long and expensive review process to gain agency approval. See Actavis, 133 S.Ct. at 2228; see also Caraco Pharm. Labs., Ltd. v. Novo Nordisk A/S, — U.S. -, 132 S.Ct. 1670, 1676, 182 L.Ed.2d 678 (2012). When a generic pharmaceutical manufacturer seeks to market a generic version of a brand-name drug, the approval process is considerably less burdensome. The Drug Price Competition and Patent Term Restoration (Hatch-Waxman) Act of 1984, 21 U.S.C. § 355, “was passed with the express purpose of expediting the entry of noninfringing generic competitors into pharmaceutical drug markets in order to decrease healthcare costs for consumers.” In re Nexium, 968 F.Supp.2d at 378. To launch a generic version of a brand-name drug, a pharmaceutical manufacturer is required to file an Abbreviated New Drug Application (“ANDA”) showing that the proposed generic product is suitably equivalent to the targeted brand drug. See 21 U.S.C. § 355(j)(2)(A)(ii)-(iv). The Hateh-Waxman Act encourages generic competition by rewarding the manufacturer that is first to file an ANDA for a brand drug. A first filer has the right, once final FDA approval is secured, to enter the generic market first and exclusively market its product for 180 days, during which time the FDA will not grant final approval to any other generic manufacturer’s version of the drug. See 21 U.S.C. § 355(j)(5)(B)(iv). The potential rewards of being a first filer are considerable. See Ralph B. Kalfayan & Vic A. Merjanian, Ensuring Access to Affordable Medication: The Supreme Court’s Opinion in F.T.C. v. Actavis, Inc., 22 Competition 120, 121 (2013) (“This 180-day exclusivity period provides a potentially powerful incentive to become the first manufacturer to file an ANDA — by some estimates, millions and perhaps billions in profits.”). Any manufacturer seeking ANDA approval, however, must “assure the FDA that its proposed generic product will not infringe” any patents related to the targeted brand drug. Novo Nordisk, 132 S.Ct. at 1676. This ostensibly is straightforward if there are no patents related to the targeted brand drug, or if those patents have or will be expired. See 21 U.S.C. § 355(j)(2)(A)(vii)(I-III). But the HatchWaxman Act also sets out a process by which a manufacturer can obtain approval to market the generic version of a brand drug before the brand drug’s underlying patents have expired. See id. § 355(j)(2)(A)(vii)(IV). To do so, a generic manufacturer’s ANDA must make so-called “Paragraph IV” certifications, which assert that all active patents related to the targeted brand drug are “invalid, unenforceable, or will not be infringed by the manufacture, use, or sale” of the applicant’s generic product. 21 C.F.R. § 314.94(a)(12)(i)(A)(4). Paragraph IV certifications usually provoke the patent-holding brand manufacturer to sue the generic ANDA filer for patent infringement. See Novo Nordisk, 132 S.Ct. at 1677 (noting that “[t]he patent statute treats [a Paragraph IV] filing as itself an act of infringement, which gives the brand [manufacturer] an immediate right to sue” (citing 35 U.S.C. § 271(e)(2)(A))). When such a lawsuit is timely filed, it triggers a 30-month stay of the generic manufacturer defendant’s ANDA, during which time it cannot receive final FDA approval of its product. See 21 U.S.C. § 355(j)(5)(B)(iii). At the end of the 30-month stay, however, the FDA may approve an ANDA even if final judgment or settlement has not been reached in the related patent lawsuit. Cf. id. If this happens, the generic manufacturer may choose to launch its generic product “at risk” — that is, with the risk of losing the infringement case against it hanging over its head. Losing an infringement case after launching at risk can result in significant liability for the generic manufacturer, as damages typically are calibrated by the amount of its at-risk sales. See 35 U.S.C. § 271(e)(4)(C) (providing that damages may be awarded “only if there has been commercial manufacture, use, offer to sell, or sale within the United States or importation into the United States of an approved drug”); 35 U.S.C. § 284 (providing for “damages adequate to compensate for the infringement, but in no event less than a reasonable royalty for the use made of the invention by the infringer”); see also, e.g., AstraZeneca AB v. Apotex Corp., 985 F.Supp.2d 452 (S.D.N.Y.2013) (awarding AstraZeneca more than $76,000,000 in damages for a generic manufacturer’s at-risk sales of a product infringing AstraZeneca’s patents). Alternately, as is the case in all civil litigation, the brand manufacturer and generic manufacturer may settle their patent infringement case before final judgment or even final FDA approval is rendered. Such a settlement can have consequences for the entire generic market, particularly when the settling generic manufacturer is the first filer and agrees to delay its generic launch. Because no other manufacturer may launch a product until 180 days after the first filer has done so, a first filer’s delay effectively delays all of its competitors’ entries, creating a bottleneck in the market that postpones the date on which any generic product will become available. To ameliorate the risk of bottleneck, the Hatch-Waxman Act contains provisions directed to triggering the start of a first filer’s 180-day exclusivity period, and to forfeiture of the privilege entirely. Generally, the exclusivity period is triggered “either on the date that the first ... filer begins marketing its generic drug, or on the date of a final court decision finding the relevant ... patents invalid or not infringed, whichever comes first.” Caraco Pharm. Labs., Ltd. v. Forest Labs., Inc., 527 F.3d 1278, 1283 (Fed.Cir.2008) (citing 21 U.S.C. § 355(j)(5)(B)(iv)). In 2003, however, Congress enacted the Medicare Prescription Drug, Improvement and Modernization Act of 2003 (“MMA”), Pub.L. No. 108-173, 117 Stat.2066, which amended the Hatch-Waxman Act to create several ways for a first filer to forfeit its marketing exclusivity period. See 21 U.S.C. § 355(j)(5)(D); see also Forest Labs., 527 F.3d at 1283 n. 2. Under the post-MMA regime, the first filers of ANDAs submitted after December 2003 lose their exclusivity privilege if they do not timely come to market after the occurrence of certain forfeiture events. Forest Labs., 527 F.3d at 1283 n. 2. One is particularly relevant to the facts of this case. The exclusivity privilege can be forfeited if the first filer does not come to market within 75 days of a final, nonappealable court judgment ruling that the first filer’s product does not infringe any of the targeted brand drug’s patents. Id. § 355(j)(5)(D)(i)(I)(bb). Moreover, “a ‘court decision’ for purposes of triggering the exclusivity period ... is not limited to actions involving the first ANDA filer.” Minnesota Mining & Mfg. Co. v. Barr Labs., Inc., 289 F.3d 775, 785 (Fed.Cir.2002) (concurring with FDA policy and Teva Pharm. v. Food & Drug Admin., 182 F.3d 1003, 1009 (D.C.Cir.1999)). It is not uncommon for generic manufacturers who submitted ANDAs after the first filer to seek declaratory judgment that the specific patents challenged in' the lawsuit against the first filer are invalid or not infringed by the first filer’s product. See generally id. at 789-92. For the second (or third or subsequent) filer, winning a declaratory judgment as to the first filer means triggering or causing the forfeiture of the first filer’s exclusivity period, moving up the date on which subsequent filers can in turn enter the market. This is one way subsequent filers can break a bottleneck formed by a first filer’s agreement to delay its market entry. 2. Undisputed Factual Background Nexium is the brand name of a proton pump inhibitor which contains esomeprazole magnesium as its active ingredient and which is prescribed to treat heartburn. In re Nexium, 968 F.Supp.2d at 375, 380. In 2001, the FDA approved a New Drug Application granting exclusive rights to market branded Nexium to the pharmaceutical manufacturer AstraZeneca, then the holder of fourteen active patents related to the drug. Id. at 380. Four years later, the generic drug manufacturer Ranbaxy was the first to file an ANDA, containing Paragraph IV certifications, to market a generic version of Nexium. Id. AstraZeneca responded to this development by filing a patent infringement lawsuit against Ranbaxy in the District of New Jersey, contending that Ranbaxy’s version of generic Nexium would infringe several of AstraZeneca’s patents. Id. In the following months, generic manufacturers Teva and DRL each filed Paragraph IV ANDAs seeking to market generic Nexium, and AstraZeneca responded again by suing each of them for patent infringement in the United States District Court for the District of New Jersey. Id. at 381. All three cases were drawn to Judge Joel A. Pisano. DRL’s Statement Undisputed Facts Regarding Mot. Summ. J. ¶¶ 70-71, ECF No. 673. Before judgment entered in any of these cases, AstraZeneca entered into settlement agreements with each generic manufacturer which ended all three lawsuits and suspended the entry of generic Nexium into the market. First, on April 14, 2008, AstraZeneca agreed to drop its lawsuit against Ranbaxy in exchange for Ranbaxy’s agreement (1) to admit that certain of AstraZeneca’s Nexium-related patents were enforceable and valid, (2) to admit that Ranbaxy’s generic Nexium would infringe these patents, and (3) to delay launching a generic version of Nexium until May 27, 2014. Id. at 381-82; see Decl. James H. Weingarten, Esq. Supp. Mots. Summ. J. (“Weingarten Decl.”), Settlement Agreement (“Ranbaxy Agreement”) 1, ECF No. 676-1. Ranbaxy allegedly also received consideration for the agreement in the form of lucrative manufacturing and distribution agreements and prospective future revenue under an exclusive marketing privilege. In re Nexium, 968 F.Supp.2d at 382. Ranbaxy’s agreement created a bottleneck in the generic Nexium market until May 27, 2014. Id. Teva and DRL each attempted to break that bottleneck by filing declaratory judgment actions seeking a ruling that Ranbaxy’s generic product did not infringe any Nexium patents, but ultimately both Teva and DRL settled their lawsuits with AstraZeneca as well. Id. at 382-83. On January 7, 2010, Teva agreed to make similar admissions as Ranbaxy had regarding AstraZeneca’s patents and to delay its entry into the generic Nexium market until May 27, 2014. Id. at 383; see Weingarten Decl., Settlement Agreement (“Teva Agreement”) 1, ECF No. 676-2. In exchange, AstraZeneca agreed to drop its lawsuit. In re Nexium, 968 F.Supp.2d at 383. On the same day, AstraZeneca also agreed to settle a contingent liability owed by Teva to AstraZeneca in connection with Teva’s prior at-risk sales of a generic drug infringing on AstraZeneca’s brand drug, Prilosec. Id. The following year, on January 28, 2011, AstraZeneca concluded a similar agreement with DRL, under the terms of which DRL agreed to refrain from challenging AstraZeneca’s Nexium patents and to defer entering the generic Nexium market until May 27, 2014. Id. at 384; see Weingarten Decl.,' Settlement Agreement (“DRL Agreement”) 1, ECF No. 676-3. In exchange, AstraZeneca dropped its litigation and on the same day, agreed to drop its appeal of a lawsuit arising from DRL’s sales of a generic version of another AstraZeneca drug, Accolate. In re Nexium, 968 F.Supp.2d at 384. II. STANDARD OF REVIEW All of the motions before the Court in this opinion are ones for summary judgment, and the same familiar standard controls them all. Summary judgment is proper when, based on the materials in the record, “there is no genuine dispute as to any material fact and the movant is entitled to judgment as a matter of law.” Fed.R.Civ.P. 56(a). An issue of material fact is genuine “if the evidence is such that a reasonable jury could return a verdict for the nonmoving party.” Anderson v. Liberty Lobby, Inc., 477 U.S. 242, 248, 106 S.Ct. 2505, 91 L.Ed.2d 202 (1986). Whether a fact is material or not depends on the substantive law of the case, and only factual disputes that might affect the outcome of the suit can properly preclude summary judgment. Id. When deciding a motion for summary judgment, the Court views the record “in the light most favorable to the non-moving party” and draws all reasonable inferences in favor of the respondent. Pineda v. Toomey, 533 F.3d 50, 53 (1st Cir.2008). Save as to facts admitted by both parties, the Court must disregard all evidence upon which the moving party bears the burden of proof. Reeves v. Sanderson Plumbing Products, Inc., 530 U.S. 133, 151, 120 S.Ct. 2097, 147 L.Ed.2d 105 (2000). Moreover, the moving party bears the initial burden of production, and then the nonmoving party who bears the ultimate burden of proof must provide some evidence in favor of its case. That evidence must be admissible at trial, and “[pjroof based on arrant speculation, optimistic surmise or farfetched inference will not suffice.” Kelly v. United States, 924 F.2d 355, 357 (1st Cir.1991). Nor can the evidence be “merely colorable.” Anderson, 477 U.S. at 249-50, 106 S.Ct. 2505. Finally, though the Court properly may consider expert testimony at the summary judgment stage, “expert testimony without ... a factual foundation cannot defeat a motion for summary judgment.” Virgin Atl. Airways Ltd. v. British Airways PLC, 69 F.Supp.2d 571, 579 (S.D.N.Y.1999) (quoting Advo, Inc. v. Phila. Newspapers, Inc., 51 F.3d 1191, 1198 (3d Cir.1995) (alteration in original)); see also Brooke Grp. Ltd. v. Brown & Williamson Tobacco Corp., 509 U.S. 209, 242, 113 S.Ct. 2578, 125 L.Ed.2d 168 (1993) (holding that an expert opinion cannot support a jury verdict when it “is not supported by sufficient facts to validate it in the eyes of the law, or where indisputable record facts contradict or otherwise render the opinion unreasonable”). Similarly, summary judgment must be granted if the opposition thereto “rest[s] solely on an expert’s ‘bottom line’ conclusion, without some underlying facts and reasons, or a logical inference process to support the expert’s opinion.” Sullivan v. Nat’l Football League, 34 F.3d 1091, 1105 (1st Cir.1994). III. MOTIONS FOR SUMMARY JUDGMENT AS TO OVERARCHING CONSPIRACY [ECF Nos. 594, 647, 905] The Court begins its analysis by focusing on the issue which most broadly affects all of the Defendants. The Defendants sought partial summary judgment last December on the issue of whether an overarching antitrust conspiracy exists among them. See DRL’s Mot. Summ. J. All Claims, ECF No. 594; AstraZeneca, Ranbaxy, & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy, ECF No. 647. According to the Plaintiffs, the three bilateral settlement agreements made between AstraZeneca and each of the Generic Defendants not only constitute separate illegal reverse payment agreements, but they also effect a single overarching conspiracy illegally to restrain trade in the market for generic Nexium. This would mean that the antitrust liability of just one Defendant is attributable to all of its co-Defendants as co-conspirators. If no such conspiracy can be reasonably inferred from the evidence, however, the Defendants are no longer yoked together by the Plaintiffs’ claims, leaving them more flexibility to litigate the antitrust issues in this case on facts specific to each individual Defendant. For the reasons set out below, the Court ruled that the Plaintiffs have met their burden of establishing a reasonable inference of overarching conspiracy. Order, Feb. 12, 2014, ¶ 3, ECF No. 857. A. Undisputed Facts Germane to These Motions As has been reviewed, AstraZeneca was the plaintiff in three Nexium-related patent infringement lawsuits against Ranbaxy, Teva, and DRL. See AstraZeneca, Ranbaxy, & Teva Defs.’ Statement Undisputed Facts Relating Mot. Partial Summ. J. Overarching Conspiracy (“Defs.’ Conspiracy SOF”) ¶¶1, 2, 9, ECF No. 687; DRL’s Statement Undisputed Facts Regarding Motion Summ. J. (“DRL’s Conspiracy SOF”) ¶52, ECF No. 673. AstraZeneca ultimately settled all three lawsuits over the course of three years: Ranbaxy settled on April 14, 2008, Defs.’ Conspiracy SOF ¶ 6, Teva settled on January 6, 2010, id. ¶ 22, and DRL settled on January 18, 2011, id. ¶ 26. See Ranbaxy Agreement 1; Teva Agreement 1; DRL Agreement 1. Several elements were common to all three agreements. Each Generic Defendant, for example, acknowledged the validity of and agreed to refrain from challenging AstraZeneca’s patents related to Nexium. See Ranbaxy Agreement ¶¶ 4.1-4.2; Teva Agreement ¶¶ 4.1 — 4.2; DRL Agreement ¶¶ 4.1-4.2. Each Generic Defendant also agreed to delay launching generic Nexium in the United States until a certain agreed-upon entry date. See Ranbaxy Agreement ¶ 6.1; Teva Agreement ¶ 6.1; DRL Agreement ¶ 6.1. Each agreement defined that entry date in nearly identical contingent terms, as the earliest of: (a) May 27, 2014; (b) the date on which a Third Party launches a Generic Esomeprazole product in the United States following a final court decision from which no appeal has been or can be taken holding that all claims of the AstraZeneca Patents asserted in that litigation are invalid, unenforceable, or not infringed by the Generic Esomeprazole product at issue in that litigation; or (c) the date prior to May 27, 2014 on which any Third Party is authorized, under a license granted by AstraZeneca ... to commence manufacturing, using, selling, offering to sell, importing- or distributing Generic Esomeprazole in and for the United States pursuant to an ANDA or application pursuant to 21 U.S.C. § 355(b)(2). Ranbaxy Agreement ¶ 5.2; see also Teva Agreement ¶ 5.2 (containing substantially similar language); DRL Agreement ¶ 5.2 (containing substantially similar language). The effect of this contingent launch provision was to commit each signing Generic Defendant to refrain from launching generic Nexium until May 27, 2014, unless another generic manufacturer found a way to legally enter the market on an earlier date. Although the terms of these agreements were all publicized shortly after their signing, there is no evidence that any of the Generic Defendants communicated with each other, directly or indirectly, when brokering their own agreements with AstraZeneca. B. Legal Standard: Antitrust Conspiracy To prevail on a conspiracy claim under Section 1 of the Sherman Act, 15 U.S.C. § 1, the Plaintiffs must prove the existence of a single agreement, tacit or express, in restraint of trade. See Bell Atl. Corp. v. Twombly, 550 U.S. 544, 553, 127 S.Ct. 1955, 167 L.Ed.2d 929 (2007); White v. R.M. Packer Co., Inc., 635 F.3d 571, 575 (1st Cir.2011). Independent decisions by individual firms, even if they constitute parallel business behavior and “lead to the same anticompetitive result as an actual agreement among market actors,” are not prohibited by the federal antitrust laws. White, 635 F.3d at 575; see also Twombly, 550 U.S. at 553, 127 S.Ct. 1955. To that end, the Supreme Court has ruled that the phenomenon of conscious parallelism is not per se illegal. See Brooke Grp., Ltd. v. Brown & Williamson Tobacco Corp., 509 U.S. 209, 227, 113 S.Ct. 2578, 125 L.Ed.2d 168 (1993); Conscious parallelism occurs when “firms in a concentrated market might in effect share monopoly power, setting their prices at a profit-maximizing, supracompetitive level by recognizing their shared interests and their interdependence with respect to price and output decisions.” Id. “Each producer may independently decide that it can maximize its profits by matching one or more other producers’ price, on the hope that the market will be able to maintain high prices if the producers do not undercut one another.” White, 635 F.3d at 576. Gas stations in a geographically isolated region, for example, are likely to engage in parallel supracompetitive pricing behavior because each gas station understands that matching the highest price in the region encourages prices to stay uniformly high without hurting demand, and that all local competitors are likely to independently reach the same conclusion. See id. at 581-82 (ruling that evidence of such «parallel pricing among gas stations on Martha’s Vineyard did not support any inference beyond conscious parallelism). “One does not need an agreement to bring about this kind of follow-the-leader effect in a concentrated industry.” Clamp-All Corp. v. Cast Iron Soil Pipe Inst., 851 F.2d 478, 484 (1st Cir.1988) (citing 6 P. Areeda & D. Turner, Antitrust Law ¶¶ 1432-33 (1978)). In contrast, a tacit agreement to conspire may be characterized by “uniform behavior among competitors, preceded by conversations implying that later uniformity might prove desirable or accompanied by other conduct that in context suggests that each competitor failed to make an independent decision.” White, 635 F.3d at 576 (quoting Brown v. Pro Football, Inc., 518 U.S. 231, 241, 116 S.Ct. 2116, 135 L.Ed.2d 521 (1996)). At the summary judgment stage, antitrust law “limit[s] the range of permissible inferences from ambiguous evidence in a [Section 1 conspiracy] case,” id. at 577, because the risk of mistaking independent, parallel decisionmaking for a conspiracy could “chill the very conduct the antitrust laws are designed to protect,” Matsushita Elec. Indus. Co., Ltd. v. Zenith Radio Corp., 475 U.S. 574, 594, 106 S.Ct. 1348, 89 L.Ed.2d 538 (1986). Accordingly, “conduct as consistent with permissible competition as with illegal conspiracy does not, standing alone, support an inference of antitrust conspiracy.” Id. (quoting Monsanto Co. v. Spray-Rite Service Corp., 465 U.S. 752, 764, 104 S.Ct. 1464, 79 L.Ed.2d 775 (1984) ' (internal quotation marks omitted)). Here, the Plaintiffs “must show that the inference of conspiracy is reasonable in light of the competing inferences of independent action or collusive action.” Id. This requires “direct or circumstantial evidence that is not only consistent with conspiracy, but ‘tends to exclude the possibility of independent action.’ ” White, 635 F.3d at 577 (quoting Monsanto Co., 465 U.S. at 764, 104 S.Ct. 1464). Circumstantial evidence meeting this standard may demonstrate, for example, “parallel behavior that would probably not result from chance, coincidence, independent responses to common stimuli, or mere interdependence unaided by an advance understanding among the parties.” Twombly, 550 U.S. at 556 n. 4, 127 S.Ct. 1955 (quoting 6 Areeda & Hovenkamp, Antitrust Law ¶ 1425, at 167 (2d ed.2003)). Pieces of evidence pointing toward conspiracy are sometimes called “plus factors.” See White, 635 F.3d at 577 (citing Twombly, 550 U.S. at 556 & n. 4, 127 S.Ct. 1955; In re Flat Glass Antitrust Litig., 385 F.3d 350, 360 (3d Cir.2004)). C. The Parties’ Arguments According to the Defendants, the Plaintiffs have failed to meet their evidentiary burden under this standard. First, the Defendants argue, the discovery process has yielded no direct evidence of discussions among AstraZeneca and the Generic Defendants suggesting a single agreement or conspiracy. Mem. Supp. AstraZeneca, Ranbaxy, & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy (“Defs.’ Conspiracy Mem.”) 6-7, ECF No. 654; see also Mem. Supp. DRL’s Mot. Summ. J. (“DRL Mem.”) 18-19, ECF No. 633; Reply Supp. AstraZeneca, Ranbaxy, & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy (“Defs.’ Conspiracy Reply Mem.”) 3, ECF No. 816; Reply Mem. Supp. DRL’s Mot. Summ. J. (“DRL Reply Mem.”) 12-17, ECF No. 819. Second, regarding potential circumstantial evidence, the Defendants point out that “[t]he existence of discrete, bilateral agreements between companies does not support an inference of an overarching agreement.” Defs.’ Conspiracy Mem. 8. They emphasize that their agreements, which were concluded “many months apart from one another and at different stages of the individual lawsuits,” id., were negotiated at arms’ length and based on the interests of the parties involved in each settlement, not on a common goal shared by the Defendants, id. at 9. They deny that “similarities” among the three agreements, or the fact that AstraZeneca was a party to all three settlements, make out a reasonable inference of interdependence. Id. The Plaintiffs, for their part, read the record quite differently. The Plaintiffs argue that at least three sets of undisputed facts constitute either direct or sufficient circumstantial evidence of a conspiracy: (1) the May 27, 2014 market entry date and “virtually identical” contingent launch clauses common to all three agreements, (2) the provisions authorizing disclosure of settlement terms to the Generic Defendants still in the midst of their own settlement negotiations, and (3) the Generic Defendants’ knowledge that delayed generic entry was anticompetitive. See Direct Purchaser & End-Payor Class Pis.’ Opp’n AstraZeneca, Ranbaxy & Teva Defs.’ Mot. Partial Summ. J. Overarching Conspiracy (ECF No. 647) & Portion DRL’s Mot. Summ. J. (ECF No. 594) (“Class Pis.’ Conspiracy Opp’n”) 3-4, 11, ECF No. 784; see also Retailer Pis.’ Mem. Opp’n AstraZeneca’s, Ranbaxy’s, & Teva’s Mot. Partial Summ. J. Pis.’ Overall Conspiracy Claim (“Retailer Pis.’ Conspiracy Opp’n”) 8, 10-11, ECF No. 746 (similarly relying on the above facts). D. Direct Evidence To start, the Court will not construe the facts offered by the Plaintiffs as direct evidence of a conspiracy. These pieces of evidence are not analogous to the types of express threats or communications that other courts have treated as direct evidence. See, e.g., Monsanto, 465 U.S. at 765, 104 S.Ct. 1464 (regarding a supplier’s advice to distributors that they would be terminated if they did not maintain suggested price levels); Mayor & City Council of Baltimore v. Citigroup, Inc., 709 F.3d 129, 136 (2d Cir.2013) (“[Direct] evidence would consist, for example, of a recorded phone call in which two competitors agreed to fix prices at a certain level.”); InterVest, Inc. v. Bloomberg, L.P., 340 F.3d 144, 163 (3d Cir.2003) (listing examples of direct evidence, including “a direct threat to the plaintiff from a competitor that if he went into business his competitors would do anything they could to stop him,” “a memorandum ... detailing the discussions from a meeting of a group of alleged conspirators,” and “a public resolution by a professional association recommending that its members withdraw their affiliation with an insurer” (quoting Intervest Fin. Servs. v. S.G. Cowen Sec. Corp., 206 F.Supp.2d 702, 713 (E.D.Pa.2002))). The Court’s conclusions are informed by the Third Circuit’s persuasive reasoning that “[d]irect evidence in [an antitrust] conspiracy must be evidence that is explicit and requires no inferences to establish the proposition or conclusion being asserted.” In re Baby Food Antitrust Litig., 166 F.3d 112, 118 (3d Cir.1999). By this logic, the evidence offered by the Plaintiffs is not direct evidence, because it does not establish, on its own, concerted action among the Defendants. Evidence of close similarities among the Defendants’ three settlements, of the Defendants’ opportunities to. conform their settlements to the others, and of the Defendants’ motives to cooperate still requires the Court to infer that illegal coordination occurred. E. Circumstantial Evidence The Plaintiffs’ evidence, particularly the settlement agreements themselves, fares much better when evaluated as circumstantial evidence of a conspiracy. 1. Interstate Circuit and Toys “R” Us While the Defendants are correct to state that “discrete, bilateral agreements” are not necessarily evidence of an overarching conspiracy, Defs.’ Conspiracy Mem. 8, courts do treat separate bilateral agreements as evidence of a single conspiracy when the agreements are sufficiently interdependent and made in the context of other plus factors suggesting coordination. In Interstate Circuit, Inc. v. United States, 306 U.S. 208, 59 S.Ct. 467, 83 L.Ed. 610 (1939), the Supreme Court considered whether a set of eight bilateral agreements between a movie exhibitor and eight movie distribution companies could constitute an illegal conspiracy. The manager of the exhibitor, Interstate, had sent a letter to all the distributors, “each letter naming all of them as addressees, in which he asked compliance with two demands as a condition of Interstate’s continued exhibition of the distributors’ films.” Id. at 215-16, 59 S.Ct. 467. All the distributors agreed to the demands. Id. at 218-19, 59 S.Ct. 467. The Supreme Court inferred not only that the exhibitor and distributors had engaged in an unlawful conspiracy, but also that no evidence of agreement among the distributors was required to sustain such an inference: It was enough that, knowing that concerted action was contemplated and invited, the distributors gave their adherence to the scheme and participated in it. Each distributor was advised that the others were asked to participate; each knew .that cooperation was essential to successful operation of the plan. They knew that the plan, if carried out, would result in a restraint of commerce .... Id. at 226, 59 S.Ct. 467. A more recent case affirming the Interstate Circuit approach to conspiracy hews even closer to the facts before this Court. In Toys “R” Us, Inc. v. Fed. Trade Comm’n, 221 F.3d 928 (7th Cir.2000), the toy retailer Toys “R” Us executed a series of agreements with individual toy manufacturers, “in each of which the manufacturer promised to restrict the distribution of its products to low-priced warehouse club stores, on the condition that other manufacturers would do the same.” Id. at 930 (emphasis added). The Seventh Circuit, reviewing a decision of the Federal Trade Commission (“F.T.C.”) under a relatively deferential substantial evidence standard, affirmed the F.T.C.’s ruling that Toys “R” Us had brokered “a network of vertical agreements,” id., constituting a horizontal agreement. Id. at 935-36. In both of these cases, interdependence was not the sole basis for an inference of conspiracy; the presiding courts also relied on the presence of plus factors suggesting that the parties were tacitly cooperating. In Interstate Circuit, the distributors knew that while lone action created “risk of a substantial loss of ... business and good will,” collective action offered “the prospect of increased profits,” creating “strong motive for concerted action.” 306 U.S. at 222, 59 S.Ct. 467. Further, their compliance with Interstate’s demands “involved a radical departure from the previous business practices of the industry.” Id. The Seventh Circuit observed these characteristics in Toys “R” Us as well, citing evidence that Toys “R” Us’s demands were against the toy manufacturers’ interests and that each manufacturer resisted committing to an agreement unless all its competitors did so. See Toys “R” Us, 221 F.3d at 936. It does not escape the Court’s notice that these cases involve a series of vertical agreements between parties at different points in the distribution chain, whereas the instant case presents a series of horizontal agreements between direct competitors. This distinction does not convince the Court that the cases are inapposite, however. The Supreme Court has affirmed that the logic of Interstate Circuit can apply to a conspiracy made up only of horizontal competitors. See United States v. Masonite Corp., 316 U.S. 265, 274-76, 62 S.Ct. 1070, 86 L.Ed. 1461 (1942) (quoting Interstate Circuit, 306 U.S. at 226, 59 S.Ct. 467) (holding that a series of independent bilateral contracts made between a hardboard manufacturer/distributor and its competitors comprised an illegal price-fixing competition). Moreover, the vertical nature of the Interstate Circuit and Toys “R” Us agreements had little bearing on the substantive reasoning of either decision. If anything, those decisions required only that the parties acquiescing to the proposed arrangement — the movie distributors and toy manufacturers — be direct competitors in a horizontal relationship with each other. See Interstate Circuit, 306 U.S. at 227, 59 S.Ct. 467 (referring to “[acceptance by competitors ... of an invitation to participate in a plan”); Toys “R” Us, 221 F.3d at 936 (“[Toys “R” Us] accomplished [its] goal by inducing the suppliers to collude, rather than to compete independently____”). This element is satisfied in the instant litigation, as all the Generic Defendants accepting AstraZeneca’s settlement were direct competitors. 2. Interdependence Like the agreements at issue in Interstate Circuit and Toys “R” Us, AstraZeneca’s agreements with the Generic Defendants demonstrate a degree of interdependence suggesting a single agreement, even if no such agreement was expressly made between the Generic Defendants. The core concession that AstraZeneca extracted from each Generic Defendant in this part of each settlement was an agreement not to enter the market until May 27, 2014. Especially in light of the significant consideration being offered by AstraZeneca through various side agreements, as well as AstraZeneca’s interest in negotiating the same entry date for all Generic Defendánts, it is not difficult to understand their agreements to delay entry as being driven by separate business decisions that happened to coincide because of “independent responses to common stimuli.” Twombly, 550 U.S. at 556 n. 4, 127 S.Ct. 1955. These concessions are, alone, as consistent with conspiracy as they are with independent action. But when the concessions are contingent on the actions of others, they are not so clearly discrete. Each Generic Defendant may have made an independent decision to sign its agreement with AstraZeneca, but it did not enter into an arrangement independent of its generic competitors. Each agreed to delay its market entry on the express condition that every other Generic Defendant do the same. See, e.g., Ranbaxy Agreement § 5.2. The Defendants attempt to frame this conditional agreement as evidence that no conspiracy existed, since the participants in a bona fide conspiracy to delay market entry would have no need for contingency provisions protecting each participant from the actions of its co-conspirators. See Defs.’ Conspiracy Reply 5. This argument seems to assume that the Plaintiffs imagine the existence of a secret, back room deal to delay market entry, which was then memorialized in three separate settlement agreements. While the Defendants are correct that such an arrangement cannot be reasonably inferred from the evidence, this is not the inference the Plaintiffs ask the Court to draw. Rather, the Court infers — as commanded by Fed.R.Civ.P. 56 — that the contingent launch clauses themselves were the mechanism of a single agreement, the means by which individual market delay concessions knit together into a network of related agreements. The interdependence of these provisions is self-evident. Without contingent launch provisions, each Generic Defendant’s agreement to delay entry until May 27, 2014 is a genuinely independent concession, setting a date that holds firm regardless of the actions of competitors. With contingent launch provisions, each Generic Defendant’s May 2014 commitment only holds firm if in concert with its competitors. There is no independence in agreeing to terms that depend on the actions of third parties in order to operate. The Court is not dissuaded by evidence that each agreement was independently negotiated and apparently settled without consultation between, any other Generic Defendant. The Defendants rely on these facts to argue that the three settlements cannot be considered a single overarching agreement. See, e.g., Defs.’ Conspiracy Mem. 8-10. In fact, no evidence of such communication among the Generic Defendants is necessary to form a Sherman Act conspiracy, nor is it even necessary for the agreements to have occurred close in time: It is elementary that an unlawful conspiracy may be and often is formed without simultaneous action or agreement on the part of the conspirators. Acceptance by competitors, without previous agreement, of an invitation to participate in a plan [restraining interstate commerce] is sufficient to establish an unlawful conspiracy under the Sherman Act. Interstate Circuit, 306 U.S. at 227, 59 S.Ct. 467 (internal citations omitted); see also Masonite, 316 U.S. at 275, 62 S.Ct. 1070 (holding a combination among Masonite and its fellow appellees to be illegal even though “each appellee, other than Masonite, acted independently of the others, negotiated only with Masonite, desired the agreement regardless of the action that might be taken by any of the others, did not require as a condition of its acceptance that Masonite make such an agreement with any of the others, and had no discussions with any of the others”). DRL makes a similar argument, arguing that the lack of agreement among the Generic Defendants is fatal to the Plaintiffs’ conspiracy claims because the Plaintiffs have alleged a “rimless wheel” conspiracy, in which AstraZeneca is the hub and the Generic Defendants are the spokes of a wheel. See DRL Mem. 18; see, e.g., Total Benefits Planning Agency, Inc. v. Anthem Blue Cross & Blue Shield, 552 F.3d 430, 435 n. 3 (6th Cir.2008). Courts in the First Circuit do not appear commonly to employ this mode of analysis in antitrust cases, but persuasive authority from other circuits holds that in order to establish such a conspiracy, the “wheel” of the alleged conspiracy must have a rim — in other words, evidence of agreement or connection between the spokes. See, e.g., In re Insurance Brokerage Antitrust Litig., 618 F.3d 300, 327 (3d Cir.2010); Total Benefits, 552 F.3d at 435-36; Dickson v. Microsoft Corp., 309 F.3d 193, 203 (4th Cir.2002); Impro Products, Inc. v. Herrick, 715 F.2d 1267, 1279-80 (8th Cir.1983). To the extent it is necessary to do so, the Court is able reasonably to infer such connections between Generic Defendants in this case. At least one court has expressly distinguished both Interstate Circuit and Toys “R” Us from rimless wheel conspiracies on grounds that are equally applicable to the Nexium agreements. In In re Insurance Brokerage Antitrust Litigation, 618 F.3d at 300, the Third Circuit reasoned that there was a rim connecting the spokes in the Interstate Circuit and Toys “R” Us arrangements because “[i]n both cases, the evidence clearly indicated that the defendants would not have undertaken their common action without reasonable assurances that all would act in concert.” Id. at 332; see also Total Benefits Planning Agency, 552 F.3d at 435-36 (asserting that the “wheel” in the Toys ‘R” Us arrangement had a rim). In the instant case, such assurances that market delay would not unduly disadvantage any one Generic Defendant were memorialized in the form of contingent launch clauses. For the purposes of the hub-and-spoke analogy, keeping in mind the presumptions required at the summary judgment stage, the Court treats the intrinsic^ interdependence of the contingent launch clauses as sufficient evidence of connection between the Generic Defendant “spokes.” 3. Plus Factors Pointing to Conspiracy Moreover, the types of plus factors that supported the rulings in Interstate Circuit and Toys “R” Us are present here. The protracted litigation between each Generic Defendant and AstraZeneca leading up to each settlement demonstrates that the Generic Defendants wanted to come to market years before May 2014. There is evidence that agreeing to delay market entry is contrary to a generic competitor’s interests, because of the potentially lucrative market for generic Nexium and the risk that by the time the generic competitor enters, the brand manufacturer will have transferred its monopoly power to a slightly reformulated product, shrinking the market for generic Nexium. See Retailer Pls.’ Conspiracy Opp’n 11; see also AstraZeneca AB v. Apotex Corp., 985 F.Supp.2d 452, 465-467 (discussing AstraZeneca’s efforts to transfer its lucrative sales of Prilosec, a branded proton pump inhibitor medication for heartburn, to Nexium, a distinct and newer branded proton pump inhibitor medication for heartburn, just before the expiration of the Prilosec patents). The record — and common sense — also shows that each Generic Defendant would be reluctant to agree to delay its entry unless AstraZeneca could secure the same guarantee of delay from all its generic competitors, lest a competitor capture the generic market before May 27, 2014. See Class Pls.’ Conspiracy Opp’n 11-12. The Defendants possessed strong motives to coordinate the actions they took. In conjunction with the interdependence of the agreements themselves, these factors are consistent with the existence of a single agreement, tend to exclude the possibility of independent action, and adequately support a reasonable inference of conspiracy. F. The In re Modafinil Litigation Since the Court’s denial of this motion in January, another court has considered these same issues and reached a different conclusion. In the consolidated litigation currently before Judge Mitchell S. Goldberg in the Eastern District of Pennsylvania, putative classes of direct purchasers, end-payors, and individual direct pharmaceutical retailers are among the plaintiffs suing a brand drug manufacturer and several generic manufacturers (including Ranbaxy and Teva), for alleged conspiracy to restrain trade in the market for a generic drug. King Drug Co. of Florence, Inc. v. Cephalon, Inc. (“In re Modafinil Litig.”), Civil Action Nos. 2:06-cv-1797, 2:06-cv-1833, 2:06-cv-2768, 2014 WL 2813312, at *1-2 (E.D.Pa. June 23, 2014). At the heart of the case are four reverse payment agreements, made between a brand manufacturer and four generic manufacturers, that settled the brand manufacturer’s pending patent infringement lawsuits relating to the brand drug Provigil. Id. at *1-3. Each generic manufacturer agreed to delay its entry into the generic Provigil market until an identical future date, unless a third party legally entered the market first. Id. at *4. As is evident and as all parties here agree, the case presents overarching conspiracy questions indistinguishable from those before this Court. See Defs.’ Submission Supp. Authority Relating Pis.’ Overarching Conspiracy Claims (“Defs.’ Modafinil Mem.”) 1, ECF No. 955; Direct Purchaser Class Pis.’ Resp. Defs.’ Submission Supp. Authority Relating Pis.’ Overarching Conspiracy Claims (“Direct Purchasers’ Modafinil Mem.”) 1, ECF No. 960. In In re Modafinil, the court ruled that the defendant pharmaceutical companies’ agreements did not constitute evidence of an illegal conspiracy and granted the defendants’ motion for summary judgment. 2014 WL 2813312, at *14. Key to Judge Goldberg’s reasoning was the conclusion that cases like “Toys “R” Us” and United States v. Apple, Inc., 952 F.Supp.2d 638 (S.D.N.Y.2013) (holding that individual agreements between book publishers and Apple, Inc. to raise the retail price of e-books constituted an illegal antitrust conspiracy), are distinguishable from the Modafinil agreement. He reasoned that unlike the toy manufacturers in Toys “R” Us and the book publishers in Apple (and, indeed, the movie distributors in Interstate Circuit), the Modafinil generic defendants entered into agreements that were in their economic interest regardless of